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- W2076180307 abstract "Belactins A and B, new inhibitors of serine carboxypeptidase were discovered in the fermentation broth of Saccharopolyspora sp. MK19–42F6. They were purified by ethyl acetate extraction, silica gel chromatography, Sephadex LH20 chromatography, Capcellpak C18 SG120 reversed phase HPLC and centrifugal partition chromatography (CPC) following their inhibitory activity against carboxypeptidase Y (CP-Y). The inhibition constants (Ki) of belactins A and B against CP-Y are 0.14 and 0.27 μM respectively. Belactins A and B have highly specific inhibitory activities for CP-Y among various peptidases, have no antimicrobial activities at 100 μ/ml and have low toxicities." @default.
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- W2076180307 date "1995-01-01" @default.
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- W2076180307 title "Belactins A and B, New Serine Carboxypeptidase Inhibitors Produced by Actinomycete. I. Taxonomy, Production, Isolation and Biological Actmties" @default.
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- W2076180307 doi "https://doi.org/10.3109/14756369509036555" @default.
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