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• W2076182323 abstract "One mismatch is discriminated in a target mRNA sequence by an inducible alkylation system based on sulfide precursors to the nucleoside 2-amino-6-vinylpurine (see scheme). The reactive oligonucleotides were delivered into the cell as poly(ethylene glycol) (PEG) conjugates in polyion-complex (PIC) micelles and showed antisense activity of high selectivity and greater potency than that of the natural antisense oligonucleotide." @default.
• W2076182323 created "2016-06-24" @default.
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• W2076182323 date "2006-04-27" @default.
• W2076182323 modified "2023-10-18" @default.
• W2076182323 title "Intracellular Inducible Alkylation System That Exhibits Antisense Effects with Greater Potency and Selectivity than the Natural Oligonucleotide" @default.
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• W2076182323 doi "https://doi.org/10.1002/anie.200504441" @default.
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• W2076182323 hasPublicationYear "2006" @default.
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