Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076183103> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2076183103 endingPage "191" @default.
- W2076183103 startingPage "184" @default.
- W2076183103 abstract "Toll-like receptors (TLRs) recognize pathogen-associated molecular patterns on microbes, and ligand recognition results in production of pro-inflammatory cytokines, reactive oxygen and nitrogen intermediates, and upregulation of costimmulatory molecules. The purpose of this study was to test antibodies specific for human or murine TLR2, 3, 4, 5 and 9 for their use in dogs. Twenty-two antibodies were assessed for recognition of canine monocytes (Mo), granulocytes (Gr) or lymphocytes (Ly) by flow cytometry, and results were compared with isotype-matched controls and other antibodies against the same TLR. Nine monoclonal antibodies detected canine leukocyte subpopulations. Antibodies TL2.1 and TL2.3 (specific for human TLR2), HTA125 (specific for human TLR4), as well as 85B152.5 and 19D759.2 (specific for human TLR5) recognized Mo and Gr but not Ly without permeabilization, and putatively cross-react with canine TLR2, 4 and 5, respectively. Antibodies 40C1285.6 and TLR3.7 (specific for human TLR3) as well as 26C593.2 and 5G5 (specific for human and murine TLR9) recognized Mo, Gr and Ly after their permeabilization and putatively cross-react with canine TLR3 and 9, respectively, inside the cell. None of these nine antibodies recognized paraformaldehyde-treated (4%) canine leukocytes but all except 40C1285.6, TLR3.7 and 5G5 recognized methanol-fixed cells, suggesting that they might be useful also in immunohistochemistry." @default.
- W2076183103 created "2016-06-24" @default.
- W2076183103 creator A5031956528 @default.
- W2076183103 creator A5070462517 @default.
- W2076183103 date "2008-07-01" @default.
- W2076183103 modified "2023-09-24" @default.
- W2076183103 title "Antibodies specific for human or murine Toll-like receptors detect canine leukocytes by flow cytometry" @default.
- W2076183103 cites W1520365933 @default.
- W2076183103 cites W1974263286 @default.
- W2076183103 cites W1987776229 @default.
- W2076183103 cites W1989978128 @default.
- W2076183103 cites W1990142540 @default.
- W2076183103 cites W2002225831 @default.
- W2076183103 cites W2022651196 @default.
- W2076183103 cites W2036767516 @default.
- W2076183103 cites W2043358582 @default.
- W2076183103 cites W2043611550 @default.
- W2076183103 cites W2051940924 @default.
- W2076183103 cites W2055969389 @default.
- W2076183103 cites W2057102446 @default.
- W2076183103 cites W2061159230 @default.
- W2076183103 cites W2069806797 @default.
- W2076183103 cites W2096743939 @default.
- W2076183103 cites W2107674270 @default.
- W2076183103 cites W2109152623 @default.
- W2076183103 cites W2115185894 @default.
- W2076183103 cites W4232031886 @default.
- W2076183103 doi "https://doi.org/10.1016/j.vetimm.2007.11.012" @default.
- W2076183103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18439687" @default.
- W2076183103 hasPublicationYear "2008" @default.
- W2076183103 type Work @default.
- W2076183103 sameAs 2076183103 @default.
- W2076183103 citedByCount "16" @default.
- W2076183103 countsByYear W20761831032012 @default.
- W2076183103 countsByYear W20761831032014 @default.
- W2076183103 countsByYear W20761831032018 @default.
- W2076183103 countsByYear W20761831032019 @default.
- W2076183103 countsByYear W20761831032023 @default.
- W2076183103 crossrefType "journal-article" @default.
- W2076183103 hasAuthorship W2076183103A5031956528 @default.
- W2076183103 hasAuthorship W2076183103A5070462517 @default.
- W2076183103 hasConcept C136449434 @default.
- W2076183103 hasConcept C142724271 @default.
- W2076183103 hasConcept C153911025 @default.
- W2076183103 hasConcept C159654299 @default.
- W2076183103 hasConcept C170493617 @default.
- W2076183103 hasConcept C203014093 @default.
- W2076183103 hasConcept C2776070231 @default.
- W2076183103 hasConcept C2776709828 @default.
- W2076183103 hasConcept C2776914184 @default.
- W2076183103 hasConcept C2778723968 @default.
- W2076183103 hasConcept C2779836521 @default.
- W2076183103 hasConcept C2781236682 @default.
- W2076183103 hasConcept C542903549 @default.
- W2076183103 hasConcept C553184892 @default.
- W2076183103 hasConcept C55493867 @default.
- W2076183103 hasConcept C71924100 @default.
- W2076183103 hasConcept C86803240 @default.
- W2076183103 hasConcept C8891405 @default.
- W2076183103 hasConceptScore W2076183103C136449434 @default.
- W2076183103 hasConceptScore W2076183103C142724271 @default.
- W2076183103 hasConceptScore W2076183103C153911025 @default.
- W2076183103 hasConceptScore W2076183103C159654299 @default.
- W2076183103 hasConceptScore W2076183103C170493617 @default.
- W2076183103 hasConceptScore W2076183103C203014093 @default.
- W2076183103 hasConceptScore W2076183103C2776070231 @default.
- W2076183103 hasConceptScore W2076183103C2776709828 @default.
- W2076183103 hasConceptScore W2076183103C2776914184 @default.
- W2076183103 hasConceptScore W2076183103C2778723968 @default.
- W2076183103 hasConceptScore W2076183103C2779836521 @default.
- W2076183103 hasConceptScore W2076183103C2781236682 @default.
- W2076183103 hasConceptScore W2076183103C542903549 @default.
- W2076183103 hasConceptScore W2076183103C553184892 @default.
- W2076183103 hasConceptScore W2076183103C55493867 @default.
- W2076183103 hasConceptScore W2076183103C71924100 @default.
- W2076183103 hasConceptScore W2076183103C86803240 @default.
- W2076183103 hasConceptScore W2076183103C8891405 @default.
- W2076183103 hasIssue "1-2" @default.
- W2076183103 hasLocation W20761831031 @default.
- W2076183103 hasLocation W20761831032 @default.
- W2076183103 hasOpenAccess W2076183103 @default.
- W2076183103 hasPrimaryLocation W20761831031 @default.
- W2076183103 hasRelatedWork W1542562771 @default.
- W2076183103 hasRelatedWork W1578002955 @default.
- W2076183103 hasRelatedWork W1897355343 @default.
- W2076183103 hasRelatedWork W1977920180 @default.
- W2076183103 hasRelatedWork W2014638089 @default.
- W2076183103 hasRelatedWork W2100704559 @default.
- W2076183103 hasRelatedWork W2151289268 @default.
- W2076183103 hasRelatedWork W2160012920 @default.
- W2076183103 hasRelatedWork W2411720109 @default.
- W2076183103 hasRelatedWork W3031425254 @default.
- W2076183103 hasVolume "124" @default.
- W2076183103 isParatext "false" @default.
- W2076183103 isRetracted "false" @default.
- W2076183103 magId "2076183103" @default.
- W2076183103 workType "article" @default.