FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076191336> ?p ?o ?g. }

• W2076191336 endingPage "204" @default.
• W2076191336 startingPage "204" @default.
• W2076191336 abstract "To the Editor:Much though I agree with the findings of Just and colleagues1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar in relation to bronchoalveolar lavage cell profiles in childhood asthma, I was disappointed that their references to the literature were far from complete. Indeed, their claim of being able to provide the first evidence that eosinophilic inflammation is related to allergic sensitization is incorrect.1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar In fact, the Belfast group, whose work the authors cite (in their reference no. 3), showed in 1997 that atopic asthmatics have significantly higher eosinophil counts than virus-associated wheezers. However, they also showed that there were significantly higher levels in atopic asthmatics than in atopic nonasthmatics. This suggests that there is more to airway eosinophilic inflammation than just allergic sensitization itself.2Stevenson EC Turner G Heaney LG Schock BC Taylor R Gallagher T et al.Bronchoalveolar lavage findings suggest two different forms of childhood asthma.Clin Exp Allergy. 1997; 27: 1027-1035Crossref PubMed Scopus (255) Google ScholarThese observations are further elaborated on in 2 studies that have measured eosinophil cationic protein levels in bronchoalveolar lavage in atopic asthmatics compared with virus-associated infant wheezers.3Ennis M Turner G Schock BC Stevenson EC Brown V Fitch PS et al.Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma.Clin Exp Allergy. 1999; 29: 362-366Crossref PubMed Scopus (57) Google Scholar, 4Marguet C Dean TP Basuyau JP Warner JO Eosinophil cationic protein and interleukin-8 levels in bronchial lavage fluid from children with asthma and infantile wheeze.Pediatr Allergy Immunol. 2001; 12: 27-33Crossref PubMed Scopus (54) Google Scholar Furthermore, there have been publications on neutrophilic inflammation in childhood in addition to those quoted by the authors in relation to adults. Indeed, the presence of neutrophilic inflammation has been directly associated with greater disease severity.5Marguet C Jouen-Boedes F Dean TP Warner JO Bronchoalveolar cell profiles in children with asthma, infantile wheeze, chronic cough or cystic fibrosis.Am J Respir Crit Care Med. 1999; 159: 1533-1540Crossref PubMed Scopus (239) Google Scholar, 6Barbato A Panizzolo C Gheno M Sainati L Favero E Faggian D et al.Bronchoalveolar lavage in asthmatic children: evidence of neutrophil activation in mild to moderate persistent asthma.Pediatr Allergy Immunol. 2001; 12: 73-77Crossref PubMed Scopus (34) Google Scholar In fact, another study showing increased neutrophil counts in infant wheezers correlated this with levels of eosinophil cationic protein. There is therefore a very clear indication from several studies that neutrophils have the potential to play a significant role in the genesis of the airway inflammation of asthma.7Azevedo I De Blic J Vargaftig BB Increased eosinophil cationic protein levels in bronchoalveolar lavage from wheezy infants.Pediatr Allergy Immunol. 2001; 12: 65-72Crossref PubMed Scopus (24) Google ScholarFinally, I think it is most important to give credit to Ferguson and colleagues,8Ferguson AC Whitelaw M Brown H Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma.J Allergy Clin Immunol. 1992; 90: 609-613Abstract Full Text PDF PubMed Scopus (132) Google Scholar who some 10 years ago were the very first investigators to demonstrate associations between bronchial eosinophilia and childhood asthma. To the Editor:Much though I agree with the findings of Just and colleagues1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar in relation to bronchoalveolar lavage cell profiles in childhood asthma, I was disappointed that their references to the literature were far from complete. Indeed, their claim of being able to provide the first evidence that eosinophilic inflammation is related to allergic sensitization is incorrect.1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar In fact, the Belfast group, whose work the authors cite (in their reference no. 3), showed in 1997 that atopic asthmatics have significantly higher eosinophil counts than virus-associated wheezers. However, they also showed that there were significantly higher levels in atopic asthmatics than in atopic nonasthmatics. This suggests that there is more to airway eosinophilic inflammation than just allergic sensitization itself.2Stevenson EC Turner G Heaney LG Schock BC Taylor R Gallagher T et al.Bronchoalveolar lavage findings suggest two different forms of childhood asthma.Clin Exp Allergy. 1997; 27: 1027-1035Crossref PubMed Scopus (255) Google ScholarThese observations are further elaborated on in 2 studies that have measured eosinophil cationic protein levels in bronchoalveolar lavage in atopic asthmatics compared with virus-associated infant wheezers.3Ennis M Turner G Schock BC Stevenson EC Brown V Fitch PS et al.Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma.Clin Exp Allergy. 1999; 29: 362-366Crossref PubMed Scopus (57) Google Scholar, 4Marguet C Dean TP Basuyau JP Warner JO Eosinophil cationic protein and interleukin-8 levels in bronchial lavage fluid from children with asthma and infantile wheeze.Pediatr Allergy Immunol. 2001; 12: 27-33Crossref PubMed Scopus (54) Google Scholar Furthermore, there have been publications on neutrophilic inflammation in childhood in addition to those quoted by the authors in relation to adults. Indeed, the presence of neutrophilic inflammation has been directly associated with greater disease severity.5Marguet C Jouen-Boedes F Dean TP Warner JO Bronchoalveolar cell profiles in children with asthma, infantile wheeze, chronic cough or cystic fibrosis.Am J Respir Crit Care Med. 1999; 159: 1533-1540Crossref PubMed Scopus (239) Google Scholar, 6Barbato A Panizzolo C Gheno M Sainati L Favero E Faggian D et al.Bronchoalveolar lavage in asthmatic children: evidence of neutrophil activation in mild to moderate persistent asthma.Pediatr Allergy Immunol. 2001; 12: 73-77Crossref PubMed Scopus (34) Google Scholar In fact, another study showing increased neutrophil counts in infant wheezers correlated this with levels of eosinophil cationic protein. There is therefore a very clear indication from several studies that neutrophils have the potential to play a significant role in the genesis of the airway inflammation of asthma.7Azevedo I De Blic J Vargaftig BB Increased eosinophil cationic protein levels in bronchoalveolar lavage from wheezy infants.Pediatr Allergy Immunol. 2001; 12: 65-72Crossref PubMed Scopus (24) Google ScholarFinally, I think it is most important to give credit to Ferguson and colleagues,8Ferguson AC Whitelaw M Brown H Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma.J Allergy Clin Immunol. 1992; 90: 609-613Abstract Full Text PDF PubMed Scopus (132) Google Scholar who some 10 years ago were the very first investigators to demonstrate associations between bronchial eosinophilia and childhood asthma. Much though I agree with the findings of Just and colleagues1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar in relation to bronchoalveolar lavage cell profiles in childhood asthma, I was disappointed that their references to the literature were far from complete. Indeed, their claim of being able to provide the first evidence that eosinophilic inflammation is related to allergic sensitization is incorrect.1Just J Fournier L Momas I Zambetti C Sahraoui F Grimfeld A Clinical significance of bronchoalveolar eosinophils in childhood asthma.J Allergy Clin Immunol. 2002; 110: 42-44Abstract Full Text Full Text PDF PubMed Scopus (37) Google Scholar In fact, the Belfast group, whose work the authors cite (in their reference no. 3), showed in 1997 that atopic asthmatics have significantly higher eosinophil counts than virus-associated wheezers. However, they also showed that there were significantly higher levels in atopic asthmatics than in atopic nonasthmatics. This suggests that there is more to airway eosinophilic inflammation than just allergic sensitization itself.2Stevenson EC Turner G Heaney LG Schock BC Taylor R Gallagher T et al.Bronchoalveolar lavage findings suggest two different forms of childhood asthma.Clin Exp Allergy. 1997; 27: 1027-1035Crossref PubMed Scopus (255) Google Scholar These observations are further elaborated on in 2 studies that have measured eosinophil cationic protein levels in bronchoalveolar lavage in atopic asthmatics compared with virus-associated infant wheezers.3Ennis M Turner G Schock BC Stevenson EC Brown V Fitch PS et al.Inflammatory mediators in bronchoalveolar lavage samples from children with and without asthma.Clin Exp Allergy. 1999; 29: 362-366Crossref PubMed Scopus (57) Google Scholar, 4Marguet C Dean TP Basuyau JP Warner JO Eosinophil cationic protein and interleukin-8 levels in bronchial lavage fluid from children with asthma and infantile wheeze.Pediatr Allergy Immunol. 2001; 12: 27-33Crossref PubMed Scopus (54) Google Scholar Furthermore, there have been publications on neutrophilic inflammation in childhood in addition to those quoted by the authors in relation to adults. Indeed, the presence of neutrophilic inflammation has been directly associated with greater disease severity.5Marguet C Jouen-Boedes F Dean TP Warner JO Bronchoalveolar cell profiles in children with asthma, infantile wheeze, chronic cough or cystic fibrosis.Am J Respir Crit Care Med. 1999; 159: 1533-1540Crossref PubMed Scopus (239) Google Scholar, 6Barbato A Panizzolo C Gheno M Sainati L Favero E Faggian D et al.Bronchoalveolar lavage in asthmatic children: evidence of neutrophil activation in mild to moderate persistent asthma.Pediatr Allergy Immunol. 2001; 12: 73-77Crossref PubMed Scopus (34) Google Scholar In fact, another study showing increased neutrophil counts in infant wheezers correlated this with levels of eosinophil cationic protein. There is therefore a very clear indication from several studies that neutrophils have the potential to play a significant role in the genesis of the airway inflammation of asthma.7Azevedo I De Blic J Vargaftig BB Increased eosinophil cationic protein levels in bronchoalveolar lavage from wheezy infants.Pediatr Allergy Immunol. 2001; 12: 65-72Crossref PubMed Scopus (24) Google Scholar Finally, I think it is most important to give credit to Ferguson and colleagues,8Ferguson AC Whitelaw M Brown H Correlation of bronchial eosinophil and mast cell activation with bronchial hyperresponsiveness in children with asthma.J Allergy Clin Immunol. 1992; 90: 609-613Abstract Full Text PDF PubMed Scopus (132) Google Scholar who some 10 years ago were the very first investigators to demonstrate associations between bronchial eosinophilia and childhood asthma." @default.
• W2076191336 created "2016-06-24" @default.
• W2076191336 creator A5050904287 @default.
• W2076191336 date "2003-01-01" @default.
• W2076191336 modified "2023-10-18" @default.
• W2076191336 title "Clinical significance of bronchoalveolar cell profiles in childhood asthma" @default.
• W2076191336 cites W1978203735 @default.
• W2076191336 cites W2020581801 @default.
• W2076191336 cites W2046854236 @default.
• W2076191336 cites W2076075374 @default.
• W2076191336 cites W2086102222 @default.
• W2076191336 cites W2116410837 @default.
• W2076191336 cites W2138589858 @default.
• W2076191336 cites W2169788953 @default.
• W2076191336 doi "https://doi.org/10.1067/mai.2003.98" @default.
• W2076191336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12532127" @default.
• W2076191336 hasPublicationYear "2003" @default.
• W2076191336 type Work @default.
• W2076191336 sameAs 2076191336 @default.
• W2076191336 citedByCount "0" @default.
• W2076191336 crossrefType "journal-article" @default.
• W2076191336 hasAuthorship W2076191336A5050904287 @default.
• W2076191336 hasBestOaLocation W20761913361 @default.
• W2076191336 hasConcept C126322002 @default.
• W2076191336 hasConcept C203014093 @default.
• W2076191336 hasConcept C2776042228 @default.
• W2076191336 hasConcept C2777714996 @default.
• W2076191336 hasConcept C2777961210 @default.
• W2076191336 hasConcept C63363279 @default.
• W2076191336 hasConcept C71924100 @default.
• W2076191336 hasConceptScore W2076191336C126322002 @default.
• W2076191336 hasConceptScore W2076191336C203014093 @default.
• W2076191336 hasConceptScore W2076191336C2776042228 @default.
• W2076191336 hasConceptScore W2076191336C2777714996 @default.
• W2076191336 hasConceptScore W2076191336C2777961210 @default.
• W2076191336 hasConceptScore W2076191336C63363279 @default.
• W2076191336 hasConceptScore W2076191336C71924100 @default.
• W2076191336 hasIssue "1" @default.
• W2076191336 hasLocation W20761913361 @default.
• W2076191336 hasLocation W20761913362 @default.
• W2076191336 hasOpenAccess W2076191336 @default.
• W2076191336 hasPrimaryLocation W20761913361 @default.
• W2076191336 hasRelatedWork W2018948120 @default.
• W2076191336 hasRelatedWork W2052139239 @default.
• W2076191336 hasRelatedWork W2374430816 @default.
• W2076191336 hasRelatedWork W2410569622 @default.
• W2076191336 hasRelatedWork W2415138818 @default.
• W2076191336 hasRelatedWork W2441567832 @default.
• W2076191336 hasRelatedWork W4235375593 @default.
• W2076191336 hasRelatedWork W4238678312 @default.
• W2076191336 hasRelatedWork W4322724676 @default.
• W2076191336 hasRelatedWork W4322728326 @default.
• W2076191336 hasVolume "111" @default.
• W2076191336 isParatext "false" @default.
• W2076191336 isRetracted "false" @default.
• W2076191336 magId "2076191336" @default.
• W2076191336 workType "article" @default.