FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076196135> ?p ?o ?g. }

• W2076196135 endingPage "1420" @default.
• W2076196135 startingPage "1415" @default.
• W2076196135 abstract "The incidence of thyroid cancer has recently experienced a rapid increase in China, and papillary thyroid carcinoma (PTC) accounts for nearly 80% of human thyroid cancers. In the present study, the differential expression of microRNAs (miRNAs) and their target genes were identified in order to analyze the potential roles of miRNAs as biomarkers and in papillary thyroid carcinogenesis. One hundred and twenty-six PTC samples were collected from patients at the China-Japan Union Hospital, China, and the gene/miRNA expression profiles were examined with Illumina BeadChips and verified by real‑time RT-PCR. Gene Ontology (GO) categories were determined, and pathway analysis was carried out using KEGG. miRNA target genes were predicted by implementing three computational analysis programs: TargetScanS, DIANA-microT and PicTar. Two hundred and forty-eight miRNAs and 3,631 genes were found to be significantly deregulated (gene, P<0.05; miRNA, P<0.01) in PTC tissues when compared with their matching normal thyroid tissues. hsa-miR-206 (target gene, MET), hsa-miR-299-3p (target gene, ITGAV), hsa-miR-101 (target gene, ITGA3), hsa-miR-103 (target gene, ITGA2), hsa-miR‑222 (target genes, KIT and AXIN2), hsa-miR-15a (target genes, AXIN2 and FOXO1) and hsa-mir-221 (target gene, KIT) were identified. Together with the functions of the target genes, we further elucidated the role of miRNAs in papillary thyroid carcinogenesis and suggest the use of miRNAs as biomarkers for early diagnosis. Our findings provide the basis for future studies in the field of miRNA-based cancer therapy." @default.
• W2076196135 created "2016-06-24" @default.
• W2076196135 creator A5011417600 @default.
• W2076196135 creator A5014528965 @default.
• W2076196135 creator A5019562881 @default.
• W2076196135 creator A5035168940 @default.
• W2076196135 creator A5035539440 @default.
• W2076196135 creator A5046045972 @default.
• W2076196135 creator A5073837776 @default.
• W2076196135 creator A5088935942 @default.
• W2076196135 date "2013-01-31" @default.
• W2076196135 modified "2023-10-16" @default.
• W2076196135 title "Expression profiles of microRNAs and their target genes in papillary thyroid carcinoma" @default.
• W2076196135 cites W1956768647 @default.
• W2076196135 cites W1967007963 @default.
• W2076196135 cites W1972755526 @default.
• W2076196135 cites W1975647849 @default.
• W2076196135 cites W1977957045 @default.
• W2076196135 cites W1981670574 @default.
• W2076196135 cites W1984534129 @default.
• W2076196135 cites W1990395674 @default.
• W2076196135 cites W1995692965 @default.
• W2076196135 cites W2002549404 @default.
• W2076196135 cites W2007987084 @default.
• W2076196135 cites W2029231027 @default.
• W2076196135 cites W2033882181 @default.
• W2076196135 cites W2040268038 @default.
• W2076196135 cites W2047682152 @default.
• W2076196135 cites W2062873714 @default.
• W2076196135 cites W2075329854 @default.
• W2076196135 cites W2092846304 @default.
• W2076196135 cites W2095272281 @default.
• W2076196135 cites W2104610341 @default.
• W2076196135 cites W2108713158 @default.
• W2076196135 cites W2110666579 @default.
• W2076196135 cites W2129468595 @default.
• W2076196135 cites W2131352095 @default.
• W2076196135 cites W2135836598 @default.
• W2076196135 cites W2137035181 @default.
• W2076196135 cites W2137456310 @default.
• W2076196135 cites W2139524845 @default.
• W2076196135 cites W2143815536 @default.
• W2076196135 cites W2144753743 @default.
• W2076196135 cites W2148200302 @default.
• W2076196135 cites W2152091242 @default.
• W2076196135 cites W2170630678 @default.
• W2076196135 doi "https://doi.org/10.3892/or.2013.2263" @default.
• W2076196135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23380809" @default.
• W2076196135 hasPublicationYear "2013" @default.
• W2076196135 type Work @default.
• W2076196135 sameAs 2076196135 @default.
• W2076196135 citedByCount "51" @default.
• W2076196135 countsByYear W20761961352013 @default.
• W2076196135 countsByYear W20761961352014 @default.
• W2076196135 countsByYear W20761961352015 @default.
• W2076196135 countsByYear W20761961352016 @default.
• W2076196135 countsByYear W20761961352017 @default.
• W2076196135 countsByYear W20761961352018 @default.
• W2076196135 countsByYear W20761961352019 @default.
• W2076196135 countsByYear W20761961352020 @default.
• W2076196135 countsByYear W20761961352021 @default.
• W2076196135 countsByYear W20761961352022 @default.
• W2076196135 countsByYear W20761961352023 @default.
• W2076196135 crossrefType "journal-article" @default.
• W2076196135 hasAuthorship W2076196135A5011417600 @default.
• W2076196135 hasAuthorship W2076196135A5014528965 @default.
• W2076196135 hasAuthorship W2076196135A5019562881 @default.
• W2076196135 hasAuthorship W2076196135A5035168940 @default.
• W2076196135 hasAuthorship W2076196135A5035539440 @default.
• W2076196135 hasAuthorship W2076196135A5046045972 @default.
• W2076196135 hasAuthorship W2076196135A5073837776 @default.
• W2076196135 hasAuthorship W2076196135A5088935942 @default.
• W2076196135 hasBestOaLocation W20761961351 @default.
• W2076196135 hasConcept C104317684 @default.
• W2076196135 hasConcept C121608353 @default.
• W2076196135 hasConcept C145059251 @default.
• W2076196135 hasConcept C150194340 @default.
• W2076196135 hasConcept C152724338 @default.
• W2076196135 hasConcept C2779761222 @default.
• W2076196135 hasConcept C2781018059 @default.
• W2076196135 hasConcept C2781461381 @default.
• W2076196135 hasConcept C29537977 @default.
• W2076196135 hasConcept C2987395477 @default.
• W2076196135 hasConcept C2993294228 @default.
• W2076196135 hasConcept C502942594 @default.
• W2076196135 hasConcept C526584372 @default.
• W2076196135 hasConcept C54355233 @default.
• W2076196135 hasConcept C555283112 @default.
• W2076196135 hasConcept C60644358 @default.
• W2076196135 hasConcept C70721500 @default.
• W2076196135 hasConcept C86803240 @default.
• W2076196135 hasConceptScore W2076196135C104317684 @default.
• W2076196135 hasConceptScore W2076196135C121608353 @default.
• W2076196135 hasConceptScore W2076196135C145059251 @default.
• W2076196135 hasConceptScore W2076196135C150194340 @default.
• W2076196135 hasConceptScore W2076196135C152724338 @default.
• W2076196135 hasConceptScore W2076196135C2779761222 @default.
• W2076196135 hasConceptScore W2076196135C2781018059 @default.

• next