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- W2076207892 abstract "Escherichia coli integration host factor (IHF) is a small dimeric protein that binds to a specific DNA consensus sequence and produces DNA bending. Transcription from the bacteriophage lambda pL promoter is stimulated three- to fourfold by IHF both in vivo and in vitro. IHF binds with high-affinity to two tandem sites located just upstream from the pL promoter and enhances the formation of RNA polymerase-promoter closed complexes. The rate of isomerization to open complex is not influenced by IHF. IHF may stimulate recognition of pL by one or more of several mechanisms: (1) by bending DNA; (2) by making protein-protein contacts with RNA polymerase; or (3) by occluding a competing promoter upstream from pL." @default.
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- W2076207892 date "1990-05-01" @default.
- W2076207892 modified "2023-09-29" @default.
- W2076207892 title "Integration host factor stimulates the phage lambda pL promoter" @default.
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- W2076207892 doi "https://doi.org/10.1016/s0022-2836(05)80124-x" @default.
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