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- W2076207954 abstract "Objective To describe a patient who developed a thyrotropin (TSH)-Secreting adenoma in the setting of primary hypothyroidism. Methods We report the clinical, laboratory, and radiologic findings of a patient with a history of primary hypothyroidism who presented with headache, a bitemporal visual field deficit, and elevated TSH despite long-term levothyroxine therapy. We discuss the diagnostic challenges of this case and review the relevant literature. Results A 54-yearold woman with a history of primary hypothyroidism presented with a 3-year history of headache and a week of worsening vision. Imaging revealed a heterogeneous sellar mass elevating the optic chiasm. Her serum TSH was 46.5 mIU/L and free thyroxine concentration was 0.1 ng/dL. The differential diagnosis included pituitary hyperplasia and a TSH-secreting adenoma in a patient with primary hypothyroidism. The pathologic characteristics of the tumor were consistent with the latter. Conclusion In a patient with an elevated TSH concentration and a previous diagnosis of hypothyroidism, it is important to consider other entities besides medication noncompliance. TSH-secreting adenomas can also cause elevated levels of TSH. (Endocr Pract. 2011;17: e135-e139)" @default.
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- W2076207954 date "2011-11-01" @default.
- W2076207954 modified "2023-09-26" @default.
- W2076207954 title "Thyrotropin-Secreting Adenoma in a Patient with Primary Hypothyroidism" @default.
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- W2076207954 doi "https://doi.org/10.4158/ep11127.cr" @default.
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