Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076220788> ?p ?o ?g. }
- W2076220788 endingPage "543" @default.
- W2076220788 startingPage "537" @default.
- W2076220788 abstract "Alkylphenol ethoxylates are widely used non-ionic surfactants. Nonylphenol ethoxylate constitutes 82% of the production of all alkylphenol ethoxylates and the breakdown product of nonylphenol ethoxylate, nonylphenol (NP) has been shown to be estrogenic in both in vitro and in vivo screening assays. To determine the potential reproductive toxicity of NP, a one-generation in utero study was conducted. Rats were dosed from gestation day 11 through 18 with NP at 3, 15, or 75 mg/kg/day or diethylstilbestrol (DES) at 30 μg/kg/day. DES was used as a positive control. Both substances were given orally by gavage. Male offspring were sacrificed at postnatal day (PND) 11, 21, or 110 and reproductive parameters were evaluated. Pup birth weight and body weight and percent motile sperm at age of 110 day were significantly reduced by DES. The absolute weight of the right epididymis was significantly reduced in the DES group. The absolute weight of the right epididymis were also significantly decreased in the animals exposed to 75 or 15 mg/kg/day NP, effects which disappeared when organ weight was related to body weight. This study showed a dose-dependent effect of nonylphenol on male reproductive development at doses of 75 and 15 mg/kg bw/day based on absolute epididymal weight." @default.
- W2076220788 created "2016-06-24" @default.
- W2076220788 creator A5029260865 @default.
- W2076220788 creator A5047254303 @default.
- W2076220788 creator A5054894074 @default.
- W2076220788 creator A5082372481 @default.
- W2076220788 creator A5083427065 @default.
- W2076220788 date "2001-09-01" @default.
- W2076220788 modified "2023-09-25" @default.
- W2076220788 title "In utero reproductive study in rats exposed to nonylphenol" @default.
- W2076220788 cites W1831301545 @default.
- W2076220788 cites W1964752987 @default.
- W2076220788 cites W1965246229 @default.
- W2076220788 cites W1967483279 @default.
- W2076220788 cites W1970230480 @default.
- W2076220788 cites W1973141811 @default.
- W2076220788 cites W1974172315 @default.
- W2076220788 cites W1982376705 @default.
- W2076220788 cites W1986310133 @default.
- W2076220788 cites W1988033322 @default.
- W2076220788 cites W1990609161 @default.
- W2076220788 cites W1991038461 @default.
- W2076220788 cites W1992273564 @default.
- W2076220788 cites W1994188772 @default.
- W2076220788 cites W1997182869 @default.
- W2076220788 cites W2002194987 @default.
- W2076220788 cites W2022932719 @default.
- W2076220788 cites W2032743237 @default.
- W2076220788 cites W2035794967 @default.
- W2076220788 cites W2043467102 @default.
- W2076220788 cites W2061947638 @default.
- W2076220788 cites W2069290661 @default.
- W2076220788 cites W2069724569 @default.
- W2076220788 cites W2073264207 @default.
- W2076220788 cites W2084346349 @default.
- W2076220788 cites W2090757999 @default.
- W2076220788 cites W2104699052 @default.
- W2076220788 cites W2118057169 @default.
- W2076220788 cites W2151635839 @default.
- W2076220788 cites W2160143312 @default.
- W2076220788 cites W2902914441 @default.
- W2076220788 cites W4236606389 @default.
- W2076220788 cites W4245397246 @default.
- W2076220788 cites W4254093939 @default.
- W2076220788 doi "https://doi.org/10.1016/s0890-6238(01)00155-1" @default.
- W2076220788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11780961" @default.
- W2076220788 hasPublicationYear "2001" @default.
- W2076220788 type Work @default.
- W2076220788 sameAs 2076220788 @default.
- W2076220788 citedByCount "49" @default.
- W2076220788 countsByYear W20762207882012 @default.
- W2076220788 countsByYear W20762207882013 @default.
- W2076220788 countsByYear W20762207882014 @default.
- W2076220788 countsByYear W20762207882015 @default.
- W2076220788 countsByYear W20762207882017 @default.
- W2076220788 countsByYear W20762207882018 @default.
- W2076220788 countsByYear W20762207882020 @default.
- W2076220788 countsByYear W20762207882021 @default.
- W2076220788 countsByYear W20762207882022 @default.
- W2076220788 crossrefType "journal-article" @default.
- W2076220788 hasAuthorship W2076220788A5029260865 @default.
- W2076220788 hasAuthorship W2076220788A5047254303 @default.
- W2076220788 hasAuthorship W2076220788A5054894074 @default.
- W2076220788 hasAuthorship W2076220788A5082372481 @default.
- W2076220788 hasAuthorship W2076220788A5083427065 @default.
- W2076220788 hasConcept C112672928 @default.
- W2076220788 hasConcept C126322002 @default.
- W2076220788 hasConcept C134018914 @default.
- W2076220788 hasConcept C147583825 @default.
- W2076220788 hasConcept C16685009 @default.
- W2076220788 hasConcept C172680121 @default.
- W2076220788 hasConcept C178790620 @default.
- W2076220788 hasConcept C185592680 @default.
- W2076220788 hasConcept C201614185 @default.
- W2076220788 hasConcept C2777227959 @default.
- W2076220788 hasConcept C2779234561 @default.
- W2076220788 hasConcept C2780155452 @default.
- W2076220788 hasConcept C2780263894 @default.
- W2076220788 hasConcept C2780862370 @default.
- W2076220788 hasConcept C2781087480 @default.
- W2076220788 hasConcept C2781254305 @default.
- W2076220788 hasConcept C2781397067 @default.
- W2076220788 hasConcept C29730261 @default.
- W2076220788 hasConcept C46699223 @default.
- W2076220788 hasConcept C46973012 @default.
- W2076220788 hasConcept C54355233 @default.
- W2076220788 hasConcept C71315377 @default.
- W2076220788 hasConcept C71924100 @default.
- W2076220788 hasConcept C86803240 @default.
- W2076220788 hasConcept C99432707 @default.
- W2076220788 hasConceptScore W2076220788C112672928 @default.
- W2076220788 hasConceptScore W2076220788C126322002 @default.
- W2076220788 hasConceptScore W2076220788C134018914 @default.
- W2076220788 hasConceptScore W2076220788C147583825 @default.
- W2076220788 hasConceptScore W2076220788C16685009 @default.
- W2076220788 hasConceptScore W2076220788C172680121 @default.
- W2076220788 hasConceptScore W2076220788C178790620 @default.
- W2076220788 hasConceptScore W2076220788C185592680 @default.