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- W2076234069 endingPage "833" @default.
- W2076234069 startingPage "821" @default.
- W2076234069 abstract "Many membrane-active peptides, such as cationic cell-penetrating peptides (CPPs) and antimicrobial peptides (AMPs), conduct their biological functions by interacting with the cell membrane. The interactions of charged residues with lipids and water facilitate membrane insertion, translocation or disruption of these highly hydrophobic species. In this review, we will summarize high-resolution structural and dynamic findings towards the understanding of the structure–activity relationship of lipid membrane-bound CPPs and AMPs, as examples of the current development of solid-state NMR (SSNMR) techniques for studying membrane peptides. We will present the most recent atomic-resolution structure of the guanidinium-phosphate complex, as constrained from experimentally measured site-specific distances. These SSNMR results will be valuable specifically for understanding the intracellular translocation pathway of CPPs and antimicrobial mechanism of AMPs, and more generally broaden our insight into how cationic macromolecules interact with and cross the lipid membrane." @default.
- W2076234069 created "2016-06-24" @default.
- W2076234069 creator A5013024407 @default.
- W2076234069 creator A5079691148 @default.
- W2076234069 creator A5082415463 @default.
- W2076234069 date "2012-10-30" @default.
- W2076234069 modified "2023-09-27" @default.
- W2076234069 title "Cationic membrane peptides: atomic-level insight of structure–activity relationships from solid-state NMR" @default.
- W2076234069 cites W1523820502 @default.
- W2076234069 cites W1554048158 @default.
- W2076234069 cites W1568327448 @default.
- W2076234069 cites W1584683177 @default.
- W2076234069 cites W1963606380 @default.
- W2076234069 cites W1964442771 @default.
- W2076234069 cites W1964937304 @default.
- W2076234069 cites W1964963882 @default.
- W2076234069 cites W1968751925 @default.
- W2076234069 cites W1970345909 @default.
- W2076234069 cites W1970621669 @default.
- W2076234069 cites W1971756197 @default.
- W2076234069 cites W1974390195 @default.
- W2076234069 cites W1983516870 @default.
- W2076234069 cites W1987614291 @default.
- W2076234069 cites W1987678987 @default.
- W2076234069 cites W1989642335 @default.
- W2076234069 cites W1989998611 @default.
- W2076234069 cites W1990069881 @default.
- W2076234069 cites W1990404775 @default.
- W2076234069 cites W1991898882 @default.
- W2076234069 cites W1993674860 @default.
- W2076234069 cites W1996685148 @default.
- W2076234069 cites W1997514647 @default.
- W2076234069 cites W1998131996 @default.
- W2076234069 cites W1999988888 @default.
- W2076234069 cites W2001683864 @default.
- W2076234069 cites W2002905222 @default.
- W2076234069 cites W2003897459 @default.
- W2076234069 cites W2005568374 @default.
- W2076234069 cites W2007446604 @default.
- W2076234069 cites W2008931830 @default.
- W2076234069 cites W2009309713 @default.
- W2076234069 cites W2010077741 @default.
- W2076234069 cites W2015326813 @default.
- W2076234069 cites W2017032430 @default.
- W2076234069 cites W2019144805 @default.
- W2076234069 cites W2020755269 @default.
- W2076234069 cites W2024293024 @default.
- W2076234069 cites W2024408347 @default.
- W2076234069 cites W2026031276 @default.
- W2076234069 cites W2026593599 @default.
- W2076234069 cites W2027808553 @default.
- W2076234069 cites W2028138612 @default.
- W2076234069 cites W2029346749 @default.
- W2076234069 cites W2030143885 @default.
- W2076234069 cites W2032148378 @default.
- W2076234069 cites W2032250529 @default.
- W2076234069 cites W2037844642 @default.
- W2076234069 cites W2043514941 @default.
- W2076234069 cites W2043936787 @default.
- W2076234069 cites W2045252225 @default.
- W2076234069 cites W2051142581 @default.
- W2076234069 cites W2052144361 @default.
- W2076234069 cites W2053785937 @default.
- W2076234069 cites W2054602599 @default.
- W2076234069 cites W2058876205 @default.
- W2076234069 cites W2060229787 @default.
- W2076234069 cites W2064287955 @default.
- W2076234069 cites W2064440346 @default.
- W2076234069 cites W2064922129 @default.
- W2076234069 cites W2065145701 @default.
- W2076234069 cites W2066743216 @default.
- W2076234069 cites W2067367618 @default.
- W2076234069 cites W2067836093 @default.
- W2076234069 cites W2068852002 @default.
- W2076234069 cites W2069076176 @default.
- W2076234069 cites W2069514224 @default.
- W2076234069 cites W2070929031 @default.
- W2076234069 cites W2072250256 @default.
- W2076234069 cites W2072721887 @default.
- W2076234069 cites W2074177096 @default.
- W2076234069 cites W2075107915 @default.
- W2076234069 cites W2075554046 @default.
- W2076234069 cites W2076406068 @default.
- W2076234069 cites W2076801702 @default.
- W2076234069 cites W2076859770 @default.
- W2076234069 cites W2078681344 @default.
- W2076234069 cites W2078884620 @default.
- W2076234069 cites W2079335891 @default.
- W2076234069 cites W2079415210 @default.
- W2076234069 cites W2079468421 @default.
- W2076234069 cites W2082204764 @default.
- W2076234069 cites W2083199597 @default.
- W2076234069 cites W2089712488 @default.
- W2076234069 cites W2091106400 @default.
- W2076234069 cites W2091807953 @default.
- W2076234069 cites W2093613982 @default.
- W2076234069 cites W2099870634 @default.
- W2076234069 cites W2105668301 @default.