FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076257543> ?p ?o ?g. }

• W2076257543 endingPage "322" @default.
• W2076257543 startingPage "315" @default.
• W2076257543 abstract "Taurine is the most abundant free amino acid in leukocytes and can react with HOBr to produce taurine bromamine (Tau-NHBr). The aim of this study was to assess the ability of Tau-NHBr to oxidize tryptophan, either free or as a residue in albumin. We have demonstrated that Tau-NHBr is a powerful oxidant for tryptophan. Importantly, in comparison to taurine chloramine, HOCl or HOBr, Tau-NHBr exhibits a degree of selectivity for tryptophan. Oxidation of albumin by Tau-NHBr resulted in emission of light, and the quantum yield was more than 10-fold more efficient than that of the other oxidants. The fluorescence band corresponding to oxidized albumin (λex 350/λem 450), which is characteristic of the formation of formylkynurenine, was significantly higher in reactions using Tau-NHBr. Excitation of the fluorescent probe 8-anilino-1-naphthalenesulfonate at 295 nm was used to assess the depletion of tryptophan residues in albumin. Results from this experiment further supported a higher efficiency of oxidation of tryptophan residues by Tau-NHBr. Other parameters of protein oxidation, including cysteine depletion and formation of carbonyl groups, were not significantly different between the oxidants tested. In conclusion, these results indicate that Tau-NHBr has a higher affinity for tryptophan residues in proteins." @default.
• W2076257543 created "2016-06-24" @default.
• W2076257543 creator A5028805841 @default.
• W2076257543 creator A5066436306 @default.
• W2076257543 creator A5075274024 @default.
• W2076257543 date "2011-03-01" @default.
• W2076257543 modified "2023-10-03" @default.
• W2076257543 title "Taurine bromamine: A potent oxidant of tryptophan residues in albumin" @default.
• W2076257543 cites W1002512956 @default.
• W2076257543 cites W1483091000 @default.
• W2076257543 cites W1508162082 @default.
• W2076257543 cites W1567614586 @default.
• W2076257543 cites W1965314635 @default.
• W2076257543 cites W1969094576 @default.
• W2076257543 cites W1969501577 @default.
• W2076257543 cites W1982561194 @default.
• W2076257543 cites W1985605238 @default.
• W2076257543 cites W1993835054 @default.
• W2076257543 cites W2012678100 @default.
• W2076257543 cites W2015744860 @default.
• W2076257543 cites W2032603811 @default.
• W2076257543 cites W2036530474 @default.
• W2076257543 cites W2043458768 @default.
• W2076257543 cites W2050486111 @default.
• W2076257543 cites W2050993447 @default.
• W2076257543 cites W2051082122 @default.
• W2076257543 cites W2058357010 @default.
• W2076257543 cites W2059325357 @default.
• W2076257543 cites W2060810203 @default.
• W2076257543 cites W2069473533 @default.
• W2076257543 cites W2070619662 @default.
• W2076257543 cites W2071170294 @default.
• W2076257543 cites W2073139930 @default.
• W2076257543 cites W2077932966 @default.
• W2076257543 cites W2083082623 @default.
• W2076257543 cites W2089491166 @default.
• W2076257543 cites W2093551079 @default.
• W2076257543 cites W2115561143 @default.
• W2076257543 cites W2154658221 @default.
• W2076257543 cites W2155608878 @default.
• W2076257543 cites W2404861852 @default.
• W2076257543 cites W4211146992 @default.
• W2076257543 cites W4235257569 @default.
• W2076257543 cites W65571157 @default.
• W2076257543 cites W989016558 @default.
• W2076257543 doi "https://doi.org/10.1016/j.abb.2010.12.026" @default.
• W2076257543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21187060" @default.
• W2076257543 hasPublicationYear "2011" @default.
• W2076257543 type Work @default.
• W2076257543 sameAs 2076257543 @default.
• W2076257543 citedByCount "19" @default.
• W2076257543 countsByYear W20762575432012 @default.
• W2076257543 countsByYear W20762575432013 @default.
• W2076257543 countsByYear W20762575432014 @default.
• W2076257543 countsByYear W20762575432015 @default.
• W2076257543 countsByYear W20762575432016 @default.
• W2076257543 countsByYear W20762575432017 @default.
• W2076257543 countsByYear W20762575432018 @default.
• W2076257543 countsByYear W20762575432020 @default.
• W2076257543 countsByYear W20762575432021 @default.
• W2076257543 countsByYear W20762575432022 @default.
• W2076257543 crossrefType "journal-article" @default.
• W2076257543 hasAuthorship W2076257543A5028805841 @default.
• W2076257543 hasAuthorship W2076257543A5066436306 @default.
• W2076257543 hasAuthorship W2076257543A5075274024 @default.
• W2076257543 hasConcept C121332964 @default.
• W2076257543 hasConcept C181199279 @default.
• W2076257543 hasConcept C185592680 @default.
• W2076257543 hasConcept C2776125364 @default.
• W2076257543 hasConcept C2776414213 @default.
• W2076257543 hasConcept C2776706248 @default.
• W2076257543 hasConcept C2779201268 @default.
• W2076257543 hasConcept C2779701627 @default.
• W2076257543 hasConcept C2781338088 @default.
• W2076257543 hasConcept C515207424 @default.
• W2076257543 hasConcept C55493867 @default.
• W2076257543 hasConcept C62520636 @default.
• W2076257543 hasConcept C71240020 @default.
• W2076257543 hasConcept C91881484 @default.
• W2076257543 hasConceptScore W2076257543C121332964 @default.
• W2076257543 hasConceptScore W2076257543C181199279 @default.
• W2076257543 hasConceptScore W2076257543C185592680 @default.
• W2076257543 hasConceptScore W2076257543C2776125364 @default.
• W2076257543 hasConceptScore W2076257543C2776414213 @default.
• W2076257543 hasConceptScore W2076257543C2776706248 @default.
• W2076257543 hasConceptScore W2076257543C2779201268 @default.
• W2076257543 hasConceptScore W2076257543C2779701627 @default.
• W2076257543 hasConceptScore W2076257543C2781338088 @default.
• W2076257543 hasConceptScore W2076257543C515207424 @default.
• W2076257543 hasConceptScore W2076257543C55493867 @default.
• W2076257543 hasConceptScore W2076257543C62520636 @default.
• W2076257543 hasConceptScore W2076257543C71240020 @default.
• W2076257543 hasConceptScore W2076257543C91881484 @default.
• W2076257543 hasFunder F4320320997 @default.
• W2076257543 hasFunder F4320322025 @default.
• W2076257543 hasIssue "2" @default.
• W2076257543 hasLocation W20762575431 @default.
• W2076257543 hasLocation W20762575432 @default.

• next