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- W2076282393 abstract "The recent comment article by Jacobson and Dietrich 1 Jacobson K. Dietrich C. Trends Cell Biol. 1999; 9: 87-91 Abstract Full Text Full Text PDF PubMed Scopus (378) Google Scholar discussed the interesting issue of the existence and physiological significance of ‘lipid rafts’. As highlighted in their article, despite considerable experimental effort, the evidence about such rafts is still equivocal. We would like to suggest, based on recent observations, that certain toxins, bacteria and viruses that bind to molecules identified as components of the proposed lipid rafts might provide experimental tools for characterization of rafts and examination of their physiological significance. As reviewed by Jacobson and Dietrich 1 Jacobson K. Dietrich C. Trends Cell Biol. 1999; 9: 87-91 Abstract Full Text Full Text PDF PubMed Scopus (378) Google Scholar and others 2 Harder T. Simons K. Curr. Opin. Cell Biol. 1997; 9: 534-542 Crossref PubMed Scopus (715) Google Scholar , 3 Edidin M. Curr. Opin. Struct. Biol. 1997; 7: 528-532 Crossref PubMed Scopus (223) Google Scholar , 4 Hooper N.M. Curr. Biol. 1998; 8: R114-R116 Abstract Full Text Full Text PDF PubMed Google Scholar , 5 Brown R.E. J. Cell Sci. 1998; 111: 1-9 Crossref PubMed Google Scholar , 6 Rietveld A. Simons K. Biochim. Biophys. Acta. 1998; 1376: 467-479 Crossref PubMed Scopus (452) Google Scholar , 7 Brown D.A. London E. Annu. Rev. Cell Dev. Biol. 1998; 14: 111-136 Crossref PubMed Scopus (2542) Google Scholar , the general view on lipid rafts is that they are enriched in glycosphingolipids, cholesterol, sphingomyelin and GPI-anchored proteins. Recent studies have shown that some of these components act as specific receptors for certain multivalent toxins, pore-forming toxins and even pathogens." @default.
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- W2076282393 title "Landing on lipid rafts" @default.
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- W2076282393 doi "https://doi.org/10.1016/s0962-8924(99)01567-6" @default.
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