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- W2076299920 abstract "Background: Craniosynostosis alters the normal growth of the infant skull and can influence intracranial pressure and intracranial volume. The purpose of this study was to measure intracranial volumes in a large series of healthy children to serve as a reference for further studies exploring the impact of craniosynostosis and vault remodeling on intracranial growth. Methods: A total of 123 children were included in this study from a retrospective review of pediatric emergency room visits for evaluation of head trauma where a head computed tomography scan was performed. Intracranial volumes were obtained using a semiautomated image segmentation technique and volume-rendering software. Results: Volume measurements were obtained and plotted against age, and a best fit curve approximation was derived. In this study of healthy children, intracranial volume doubled by 9 months of age and tripled by 6 years of age. Conclusions: This large study contributes to the existing data demonstrating intracranial volumes in healthy children up to 6 years of age. These data can be used by clinicians as a reference in the assessment of a child presenting with cranial dysmorphology." @default.
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- W2076299920 date "2009-12-01" @default.
- W2076299920 modified "2023-10-11" @default.
- W2076299920 title "Intracranial Volumes in a Large Series of Healthy Children" @default.
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- W2076299920 doi "https://doi.org/10.1097/prs.0b013e3181bcefc4" @default.
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