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- W2076317085 abstract "The death receptor Fas is a member of the tumor necrosis factor receptor family; upon interaction with its ligand it efficiently activates caspases and induces apoptosis. Despite abundant Fas surface expression, however, Fas death-signals are frequently interrupted. Many viruses express antiapoptotic proteins, including caspase inhibitors, Bcl-2 homologues and death-effector-domain-containing proteins that are termed FLIPs (FLICE [Fas-associated death-domain-like IL-1β-converting enzyme]-inhibitory proteins). Cellular homologues of these inhibitors have been identified. Cellular FLIPs structurally resemble caspase-8 except that they lack proteolytic activity. FLIPs are highly expressed in tumor cells, T lymphocytes and healthy, but not injured, myocytes; this suggests a critical role of FLIPs as endogenous modulators of apoptosis." @default.
- W2076317085 created "2016-06-24" @default.
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- W2076317085 creator A5059727262 @default.
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- W2076317085 date "1998-10-01" @default.
- W2076317085 modified "2023-10-10" @default.
- W2076317085 title "Inhibition of Fas death signals by FLIPs" @default.
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- W2076317085 cites W1516581843 @default.
- W2076317085 cites W1521538212 @default.
- W2076317085 cites W1535874622 @default.
- W2076317085 cites W1581871973 @default.
- W2076317085 cites W1587890084 @default.
- W2076317085 cites W1589415602 @default.
- W2076317085 cites W1772617136 @default.
- W2076317085 cites W1836073275 @default.
- W2076317085 cites W1969771851 @default.
- W2076317085 cites W1972805802 @default.
- W2076317085 cites W1973109581 @default.
- W2076317085 cites W1974351164 @default.
- W2076317085 cites W1975291295 @default.
- W2076317085 cites W1975336660 @default.
- W2076317085 cites W1975670576 @default.
- W2076317085 cites W1975870295 @default.
- W2076317085 cites W1978018492 @default.
- W2076317085 cites W1979444649 @default.
- W2076317085 cites W1980754795 @default.
- W2076317085 cites W1982784171 @default.
- W2076317085 cites W1983532054 @default.
- W2076317085 cites W1985138230 @default.
- W2076317085 cites W1992637685 @default.
- W2076317085 cites W1994266361 @default.
- W2076317085 cites W1995679586 @default.
- W2076317085 cites W1995871393 @default.
- W2076317085 cites W1996980134 @default.
- W2076317085 cites W2002154440 @default.
- W2076317085 cites W2002503549 @default.
- W2076317085 cites W2002507218 @default.
- W2076317085 cites W2006888084 @default.
- W2076317085 cites W2013545866 @default.
- W2076317085 cites W2013801793 @default.
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- W2076317085 cites W2017728303 @default.
- W2076317085 cites W2017985723 @default.
- W2076317085 cites W2019450833 @default.
- W2076317085 cites W2021427686 @default.
- W2076317085 cites W2021943787 @default.
- W2076317085 cites W2028111124 @default.
- W2076317085 cites W2035523654 @default.
- W2076317085 cites W2040624923 @default.
- W2076317085 cites W2044202608 @default.
- W2076317085 cites W2045796964 @default.
- W2076317085 cites W2045923190 @default.
- W2076317085 cites W2049110705 @default.
- W2076317085 cites W2055588490 @default.
- W2076317085 cites W2058773384 @default.
- W2076317085 cites W2060057046 @default.
- W2076317085 cites W2060203869 @default.
- W2076317085 cites W2065413461 @default.
- W2076317085 cites W2070352944 @default.
- W2076317085 cites W2074280352 @default.
- W2076317085 cites W2076229621 @default.
- W2076317085 cites W2077705257 @default.
- W2076317085 cites W2085173450 @default.
- W2076317085 cites W2087079563 @default.
- W2076317085 cites W2087593127 @default.
- W2076317085 cites W2087669979 @default.
- W2076317085 cites W2089476060 @default.
- W2076317085 cites W2092508425 @default.
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- W2076317085 cites W2113505777 @default.
- W2076317085 cites W2119299816 @default.
- W2076317085 cites W2120492514 @default.
- W2076317085 cites W2128558120 @default.
- W2076317085 cites W2154757961 @default.
- W2076317085 cites W2167523718 @default.
- W2076317085 cites W2168945225 @default.
- W2076317085 cites W4241091303 @default.
- W2076317085 cites W4250256124 @default.
- W2076317085 doi "https://doi.org/10.1016/s0952-7915(98)80223-9" @default.
- W2076317085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9794838" @default.
- W2076317085 hasPublicationYear "1998" @default.
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