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- W2076322051 abstract "Disintegration tests were performed on tablets compressed from 16/20, 40/60, and 60/80 mesh granulations prepared by the method of dry granulation to contain 250 mg. of tolbutamide and corn starch concentrations of 6, 7, 8, 9, and 10 percent in each granulation size. It might be expected that disintegration time would decrease as the percentage of starch in the tablet increased. This does not appear to be the case for tolbutamide tablets. Instead, there appears to be a critical starch concentration for different granulation sizes. Disintegration tests were performed on tablets compressed from 16/20, 40/60, and 60/80 mesh granulations prepared by the method of dry granulation to contain 250 mg. of tolbutamide and corn starch concentrations of 6, 7, 8, 9, and 10 percent in each granulation size. It might be expected that disintegration time would decrease as the percentage of starch in the tablet increased. This does not appear to be the case for tolbutamide tablets. Instead, there appears to be a critical starch concentration for different granulation sizes." @default.
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- W2076322051 date "1968-07-01" @default.
- W2076322051 modified "2023-09-26" @default.
- W2076322051 title "Influence of Starch Concentration on the Disintegration Time of Tolbutamide Tablets" @default.
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- W2076322051 doi "https://doi.org/10.1002/jps.2600570744" @default.
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