Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076336230> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2076336230 endingPage "848" @default.
- W2076336230 startingPage "841" @default.
- W2076336230 abstract "To examine whether insulin during infancy affects later glucose regulation, 60 rat pups of both sexes were injected daily on postnatal Days 9-20 with either insulin (2 or 8 U/kg), 2-deoxy-D-glucose (2DG; 200 or 400 mg/kg), or saline. Two hours postinjection on Day 15, pups given insulin were hypoglycemic and pups given 2DG were hyperglycemic; both groups were normoglycemic at 6 h. The two insulin doses produced similar long-term effects, as did the 2DG doses, so doses were combined to make single insulin and 2DG groups. On Day 44, baseline plasma glucose for rats given insulin or 2DG during infancy was below saline control levels (111.3, 114.5, and 120.7 mg/dL, respectively, p < 0.05). On Days 60 and 62, plasma glucose was assessed 2 h after injection of 3 U/kg insulin; food was allowed between the insulin injection and the glucose test on only one of these days. When food was present after injection of insulin, the early treatments did not influence either amount of food ingested or plasma glucose levels. When food was withheld, however, males given insulin before weaning maintained a higher plasma glucose than did males given 2DG or saline before weaning (67.4, 40.1, and 16.4 mg/dL, respectively, p < 0.01); females were unaffected by the early treatment. Postweaning body weights did not differ from control values for rats given early insulin or 2DG. On Day 72, there were no effects of early treatment on plasma insulin, plasma glucose, liver weight, or kidney weight. These results suggest that preweaning exposure to insulin attenuates the hypoglycemia of adult males given insulin without food." @default.
- W2076336230 created "2016-06-24" @default.
- W2076336230 creator A5000791777 @default.
- W2076336230 creator A5016743403 @default.
- W2076336230 creator A5027250777 @default.
- W2076336230 date "1997-10-01" @default.
- W2076336230 modified "2023-09-25" @default.
- W2076336230 title "Insulin During Infancy Attenuates Insulin-Induced Hypoglycemia in Adult Male Rats" @default.
- W2076336230 cites W1536070820 @default.
- W2076336230 cites W1904427021 @default.
- W2076336230 cites W1968882817 @default.
- W2076336230 cites W1976850923 @default.
- W2076336230 cites W1977674017 @default.
- W2076336230 cites W1994758008 @default.
- W2076336230 cites W2000992390 @default.
- W2076336230 cites W2005960694 @default.
- W2076336230 cites W2019563294 @default.
- W2076336230 cites W2024841698 @default.
- W2076336230 cites W2028906997 @default.
- W2076336230 cites W2039197495 @default.
- W2076336230 cites W2043889745 @default.
- W2076336230 cites W2053322498 @default.
- W2076336230 cites W2055471624 @default.
- W2076336230 cites W2072698475 @default.
- W2076336230 cites W2084664396 @default.
- W2076336230 cites W2085595419 @default.
- W2076336230 cites W2093956336 @default.
- W2076336230 cites W2094244604 @default.
- W2076336230 cites W2096141110 @default.
- W2076336230 cites W2134787033 @default.
- W2076336230 cites W2141089991 @default.
- W2076336230 cites W2148822696 @default.
- W2076336230 cites W2151210826 @default.
- W2076336230 cites W2277293588 @default.
- W2076336230 cites W2282708282 @default.
- W2076336230 cites W2293810878 @default.
- W2076336230 cites W2315317701 @default.
- W2076336230 cites W2335368931 @default.
- W2076336230 cites W2338754602 @default.
- W2076336230 cites W2407962055 @default.
- W2076336230 cites W2420522141 @default.
- W2076336230 cites W4236751371 @default.
- W2076336230 cites W4253766026 @default.
- W2076336230 cites W2064452382 @default.
- W2076336230 doi "https://doi.org/10.1016/s0031-9384(97)00247-3" @default.
- W2076336230 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9284506" @default.
- W2076336230 hasPublicationYear "1997" @default.
- W2076336230 type Work @default.
- W2076336230 sameAs 2076336230 @default.
- W2076336230 citedByCount "4" @default.
- W2076336230 countsByYear W20763362302015 @default.
- W2076336230 crossrefType "journal-article" @default.
- W2076336230 hasAuthorship W2076336230A5000791777 @default.
- W2076336230 hasAuthorship W2076336230A5016743403 @default.
- W2076336230 hasAuthorship W2076336230A5027250777 @default.
- W2076336230 hasConcept C126322002 @default.
- W2076336230 hasConcept C134018914 @default.
- W2076336230 hasConcept C2777391703 @default.
- W2076336230 hasConcept C2777397205 @default.
- W2076336230 hasConcept C2779306644 @default.
- W2076336230 hasConcept C2780352109 @default.
- W2076336230 hasConcept C2780655333 @default.
- W2076336230 hasConcept C2780668416 @default.
- W2076336230 hasConcept C71924100 @default.
- W2076336230 hasConceptScore W2076336230C126322002 @default.
- W2076336230 hasConceptScore W2076336230C134018914 @default.
- W2076336230 hasConceptScore W2076336230C2777391703 @default.
- W2076336230 hasConceptScore W2076336230C2777397205 @default.
- W2076336230 hasConceptScore W2076336230C2779306644 @default.
- W2076336230 hasConceptScore W2076336230C2780352109 @default.
- W2076336230 hasConceptScore W2076336230C2780655333 @default.
- W2076336230 hasConceptScore W2076336230C2780668416 @default.
- W2076336230 hasConceptScore W2076336230C71924100 @default.
- W2076336230 hasIssue "4" @default.
- W2076336230 hasLocation W20763362301 @default.
- W2076336230 hasLocation W20763362302 @default.
- W2076336230 hasOpenAccess W2076336230 @default.
- W2076336230 hasPrimaryLocation W20763362301 @default.
- W2076336230 hasRelatedWork W1967954429 @default.
- W2076336230 hasRelatedWork W2000308085 @default.
- W2076336230 hasRelatedWork W2001044066 @default.
- W2076336230 hasRelatedWork W2029049751 @default.
- W2076336230 hasRelatedWork W2033840628 @default.
- W2076336230 hasRelatedWork W2034707862 @default.
- W2076336230 hasRelatedWork W2048352852 @default.
- W2076336230 hasRelatedWork W2089387278 @default.
- W2076336230 hasRelatedWork W2095179743 @default.
- W2076336230 hasRelatedWork W2124759347 @default.
- W2076336230 hasVolume "62" @default.
- W2076336230 isParatext "false" @default.
- W2076336230 isRetracted "false" @default.
- W2076336230 magId "2076336230" @default.
- W2076336230 workType "article" @default.