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- W2076342207 abstract "BACKGROUND AND OBJECTIVE: To investigate the relationship between retinal vessel morphology (branching coefficient, bifurcation angle, and fractal analysis) and retinal nerve fiber layer (RNFL) thickness in an elderly population. PATIENTS AND METHODS: One hundred and one participants from the Lothian Birth Cohort 1936 (population of people all born in 1936) were studied. RNFL thickness measurements (using optical coherence tomography [OCT]) and digital retinal photographs were collected. The retinal images were analyzed using custom-designed software called the Vascular Assessment and Measurement Platform for Images of the Retina. RESULTS: Greater deviation from the optimal arteriolar branching coefficient was associated with greater RNFL thickness ( r = 0.249, P = .028). There was no significant association between RNFL thickness and the other retinal vessel morphology parameters. CONCLUSION: RNFL thickness increased significantly with suboptimality of arteriole branching coefficient. These findings cannot be explained by our current understanding of OCT. OCT-based biomarker metrics require further study to better define retinal neurovascular imaging and anatomy." @default.
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- W2076342207 date "2012-11-01" @default.
- W2076342207 modified "2023-09-25" @default.
- W2076342207 title "The Association Between Retinal Vessel Morphology and Retinal Nerve Fiber Layer Thickness in an Elderly Population" @default.
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- W2076342207 doi "https://doi.org/10.3928/15428877-20120802-03" @default.
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