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• W2076349775 abstract "Polymeric-DNA complexes (polyplexes) are constructed with multiple layers of counter-polyions as DNA/polyethylenimine/poly(acrylic acid)/polyethylenimine. The increased association of polyethylenimine achieved by the multilayer approach leads to substantial increases in expression of transgene for reporter plasmids without the need for excess free polymer typically required for non-viral gene delivery. This method of polyplex preparation provides the opportunity to improve transgene expression for gene therapy approaches to disease treatment. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/c0633_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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• W2076349775 date "2008-01-07" @default.
• W2076349775 modified "2023-09-27" @default.
• W2076349775 title "Multilayer Nanocomplexes of Polymer and DNA Exhibit Enhanced Gene Delivery" @default.
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• W2076349775 doi "https://doi.org/10.1002/adma.200700633" @default.
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