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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076351150> ?p ?o ?g. }

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• W2076351150 abstract "Galactose moiety as the hepatocyte anchorage was covalently coupled with chitosan for the development of synthetic extracellular matrix. Hepatocytes adhesion to galactosylated chitosan (GC)-coated polystyrene (PS) dish became as high as 94.7% after 2 h incubation whereas the hepatocytes adhesion to chitosan-coated PS dish was 69.1%, indication of galactose-specific recognition between GC molecules and asialoglycoprotein receptors of hepatocytes. The DNA synthesis of the hepatocytes adhered to GC-coated dish was increased in the presence of epidermal growth factor (EGF) at low concentration of GC (0.05 μg/ml) whereas the DNA synthesis of the hepatocytes adhered to GC-coated dish was decreased in the presence of EGF at high concentration of GC (5 μg/ml). The spreading shapes of the hepatocytes adhered to the surface in the presence of EGF at low concentration of GC (0.05 μg/ml) were enhanced than in the absence of EGF. The hepatocytes adhered to the surface at high concentration of GC (5 μg/ml) showed round shapes and exhibited many spheroid formation after 24 h in the presence of EGF." @default.
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• W2076351150 date "2003-06-01" @default.
• W2076351150 modified "2023-09-26" @default.
• W2076351150 title "Galactosylated chitosan as a synthetic extracellular matrix for hepatocytes attachment" @default.
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• W2076351150 doi "https://doi.org/10.1016/s0142-9612(03)00108-x" @default.
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