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- W2076383445 abstract "ABSTRACT The high rates of mutation, recombination, and replication drive HIV-1 diversity. In this study, we investigated how cell type affects viral mutation rate and mutation spectra. In studying four different cell types, no differences in mutation rate were observed, but intriguingly cell type differences impacted HIV-1 mutation spectra. This is the first description of significant differences in HIV-1 mutation spectra observed in different cell types in the absence of changes in the viral mutation rate." @default.
- W2076383445 created "2016-06-24" @default.
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- W2076383445 date "2013-05-01" @default.
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- W2076383445 title "Variation of HIV-1 Mutation Spectra among Cell Types" @default.
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- W2076383445 doi "https://doi.org/10.1128/jvi.03576-12" @default.
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