FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076388225> ?p ?o ?g. }

• W2076388225 endingPage "2496" @default.
• W2076388225 startingPage "2486" @default.
• W2076388225 abstract "In Saccharomyces cerevisiae , disruption of the YCF1 gene increases the sensitivity of cell growth to mercury. Transformation of the resulting ycf1 null mutant with a plasmid harbouring YCF1 under the control of the GAL promoter largely restores the wild‐type resistance to the metal ion. The protective effect of Ycf1p against the toxicity of mercury is especially pronounced when yeast cells are grown in rich medium or in minimal medium supplemented with glutathione. Secretory vesicles from S. cerevisiae cells overproducing Ycf1p are shown to exhibit ATP‐dependent transport of bis(glutathionato)mercury. Moreover, using β‐galactosidase as a reporter protein, a relationship between mercury addition and the activity of the YCF1 promoter can be shown. Altogether, these observations indicate a defence mechanism involving an induction of the expression of Ycf1p and transport by this protein of mercury–glutathione adducts into the vacuole. Finally, possible coparticipation in mercury tolerance of other ABC proteins sharing close homology with Ycf1p was investigated. Gene disruption experiments enable us to conclude that neither Bpt1p, Yor1p, Ybt1p nor YHL035p plays a major role in the detoxification of mercury." @default.
• W2076388225 created "2016-06-24" @default.
• W2076388225 creator A5029640814 @default.
• W2076388225 creator A5036765563 @default.
• W2076388225 creator A5049241669 @default.
• W2076388225 creator A5049884097 @default.
• W2076388225 creator A5049987772 @default.
• W2076388225 creator A5057517397 @default.
• W2076388225 creator A5086640603 @default.
• W2076388225 date "2003-05-14" @default.
• W2076388225 modified "2023-10-14" @default.
• W2076388225 title "Ycf1p-dependent Hg(II) detoxification in Saccharomyces cerevisiae" @default.
• W2076388225 cites W124099229 @default.
• W2076388225 cites W1510288506 @default.
• W2076388225 cites W1521778811 @default.
• W2076388225 cites W1530873901 @default.
• W2076388225 cites W1543459633 @default.
• W2076388225 cites W1578589309 @default.
• W2076388225 cites W1779239456 @default.
• W2076388225 cites W1842523267 @default.
• W2076388225 cites W1863237001 @default.
• W2076388225 cites W1919698428 @default.
• W2076388225 cites W1941077906 @default.
• W2076388225 cites W1969737313 @default.
• W2076388225 cites W1985910275 @default.
• W2076388225 cites W1990620985 @default.
• W2076388225 cites W1996406807 @default.
• W2076388225 cites W2000250937 @default.
• W2076388225 cites W2009361400 @default.
• W2076388225 cites W2042798506 @default.
• W2076388225 cites W2045627528 @default.
• W2076388225 cites W2057865646 @default.
• W2076388225 cites W2065852288 @default.
• W2076388225 cites W2077105280 @default.
• W2076388225 cites W2077587123 @default.
• W2076388225 cites W2080408951 @default.
• W2076388225 cites W2081663028 @default.
• W2076388225 cites W2084508391 @default.
• W2076388225 cites W2084509716 @default.
• W2076388225 cites W2086660631 @default.
• W2076388225 cites W2087334270 @default.
• W2076388225 cites W2091297151 @default.
• W2076388225 cites W2100057937 @default.
• W2076388225 cites W2122074467 @default.
• W2076388225 cites W2130097356 @default.
• W2076388225 cites W2131118500 @default.
• W2076388225 cites W2135541075 @default.
• W2076388225 cites W2146932296 @default.
• W2076388225 cites W2147756213 @default.
• W2076388225 cites W2162009972 @default.
• W2076388225 cites W2168095256 @default.
• W2076388225 cites W2169333620 @default.
• W2076388225 cites W2169357831 @default.
• W2076388225 cites W2324365361 @default.
• W2076388225 cites W2338811717 @default.
• W2076388225 cites W2407723082 @default.
• W2076388225 cites W2756110755 @default.
• W2076388225 cites W4243850575 @default.
• W2076388225 cites W4362234548 @default.
• W2076388225 cites W4376848496 @default.
• W2076388225 doi "https://doi.org/10.1046/j.1432-1033.2003.03620.x" @default.
• W2076388225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12755704" @default.
• W2076388225 hasPublicationYear "2003" @default.
• W2076388225 type Work @default.
• W2076388225 sameAs 2076388225 @default.
• W2076388225 citedByCount "76" @default.
• W2076388225 countsByYear W20763882252012 @default.
• W2076388225 countsByYear W20763882252013 @default.
• W2076388225 countsByYear W20763882252014 @default.
• W2076388225 countsByYear W20763882252015 @default.
• W2076388225 countsByYear W20763882252016 @default.
• W2076388225 countsByYear W20763882252018 @default.
• W2076388225 countsByYear W20763882252019 @default.
• W2076388225 countsByYear W20763882252020 @default.
• W2076388225 countsByYear W20763882252021 @default.
• W2076388225 countsByYear W20763882252022 @default.
• W2076388225 countsByYear W20763882252023 @default.
• W2076388225 crossrefType "journal-article" @default.
• W2076388225 hasAuthorship W2076388225A5029640814 @default.
• W2076388225 hasAuthorship W2076388225A5036765563 @default.
• W2076388225 hasAuthorship W2076388225A5049241669 @default.
• W2076388225 hasAuthorship W2076388225A5049884097 @default.
• W2076388225 hasAuthorship W2076388225A5049987772 @default.
• W2076388225 hasAuthorship W2076388225A5057517397 @default.
• W2076388225 hasAuthorship W2076388225A5086640603 @default.
• W2076388225 hasBestOaLocation W20763882251 @default.
• W2076388225 hasConcept C102568950 @default.
• W2076388225 hasConcept C104317684 @default.
• W2076388225 hasConcept C143065580 @default.
• W2076388225 hasConcept C181199279 @default.
• W2076388225 hasConcept C185592680 @default.
• W2076388225 hasConcept C190062978 @default.
• W2076388225 hasConcept C199360897 @default.
• W2076388225 hasConcept C22744801 @default.
• W2076388225 hasConcept C2777576037 @default.
• W2076388225 hasConcept C2777777548 @default.
• W2076388225 hasConcept C2779222958 @default.
• W2076388225 hasConcept C41008148 @default.

• next