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• W2076398105 abstract "Maytenus aquifolium (Celastraceae) and Salacia campestris (Hippocrateaceae) species accumulate friedelane and quinonemethide triterpenoids in their leaves and root bark, respectively. Enzymatic extracts obtained from leaves displayed cyclase activity with conversion of the substrate oxidosqualene to the triterpenes, 3β-friedelanol and friedelin. In addition, administration of (±)5-3H mevalonolactone in leaves of M. aquifolium seedlings produced radio labelled friedelin in the leaves, twigs and stems, while the root bark accumulated labelled maytenin and pristimerin. These experiments indicated that the triterpenes once biosynthesized in the leaves are translocated to the root bark and further transformed to the antitumoral quinonemethide triterpenoids." @default.
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• W2076398105 date "2000-12-01" @default.
• W2076398105 modified "2023-10-15" @default.
• W2076398105 title "Biosynthesis of friedelane and quinonemethide triterpenoids is compartmentalized in Maytenus aquifolium and Salacia campestris" @default.
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• W2076398105 doi "https://doi.org/10.1016/s0031-9422(00)00285-5" @default.
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