Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076413450> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2076413450 abstract "Background: The most common ocular neoplasm in children is retinoblastoma which can spreads to the brain via the optic nerve in untreated patients. The most common treatment is enucleation, but modern eye-preserving therapies may save the globe. In advanced stages, globe-preserving strategies are often insufficient to prevent enucleation and direct infusion of chemotherapeutic agents into the ophthalmic artery may be required to control the tumor. Objectives: In this presentation, we aim to report our experience about the safety and efficacy of intra-ophthalmic artery melphalan (IAM) injection in the treatment of retinoblastoma. : Patients and Methods: Totally 46 patients were enrolled into the study. Mean age was 36.8 + 22.2 months (7100 months). Using digital subtraction angiography, under roadmap guidance a microcatheter was introduced into the ophthalmic artery, subsequently melphalan was injected over 3040 minutes. The response of the retinoblastoma tumor(s) and any associated local side effects of the treatment were observed. Results: Twenty-three patients were male (50%). Mean weight was 11.2 + 3.9 Kg (420) and mean height was 89.3 + 16.2 cm (65110). The disease was in the right eye in 19 patients (41.3%), left eye in 23 patients (50%) and bilateral in 3 patients (6.5%). The ophthalmic arteries were successfully cannulated except in one patient. There were not severe systemic side effects in our patients. Vasospasm happened in one patient. Canulization failed in one patient out of 29 (3.4%). Conclusions: Intra-arterial melphalan injection into the ophthalmic artery is an effective and safe therapeutic modality for retinoblastoma." @default.
- W2076413450 created "2016-06-24" @default.
- W2076413450 creator A5000606748 @default.
- W2076413450 creator A5052505309 @default.
- W2076413450 creator A5055403001 @default.
- W2076413450 creator A5079440390 @default.
- W2076413450 creator A5085270969 @default.
- W2076413450 date "2014-03-01" @default.
- W2076413450 modified "2023-09-26" @default.
- W2076413450 title "Safety and Efficacy of Intra-Arterial Chemotherapy in Retinoblastoma" @default.
- W2076413450 doi "https://doi.org/10.5812/iranjradiol.21432" @default.
- W2076413450 hasPublicationYear "2014" @default.
- W2076413450 type Work @default.
- W2076413450 sameAs 2076413450 @default.
- W2076413450 citedByCount "0" @default.
- W2076413450 crossrefType "journal-article" @default.
- W2076413450 hasAuthorship W2076413450A5000606748 @default.
- W2076413450 hasAuthorship W2076413450A5052505309 @default.
- W2076413450 hasAuthorship W2076413450A5055403001 @default.
- W2076413450 hasAuthorship W2076413450A5079440390 @default.
- W2076413450 hasAuthorship W2076413450A5085270969 @default.
- W2076413450 hasBestOaLocation W20764134501 @default.
- W2076413450 hasConcept C104317684 @default.
- W2076413450 hasConcept C118487528 @default.
- W2076413450 hasConcept C126838900 @default.
- W2076413450 hasConcept C141071460 @default.
- W2076413450 hasConcept C158846371 @default.
- W2076413450 hasConcept C185592680 @default.
- W2076413450 hasConcept C188261085 @default.
- W2076413450 hasConcept C2776406671 @default.
- W2076413450 hasConcept C2776577112 @default.
- W2076413450 hasConcept C2776694085 @default.
- W2076413450 hasConcept C2778286760 @default.
- W2076413450 hasConcept C2778684742 @default.
- W2076413450 hasConcept C2780643987 @default.
- W2076413450 hasConcept C2780662894 @default.
- W2076413450 hasConcept C2781092963 @default.
- W2076413450 hasConcept C55493867 @default.
- W2076413450 hasConcept C71924100 @default.
- W2076413450 hasConceptScore W2076413450C104317684 @default.
- W2076413450 hasConceptScore W2076413450C118487528 @default.
- W2076413450 hasConceptScore W2076413450C126838900 @default.
- W2076413450 hasConceptScore W2076413450C141071460 @default.
- W2076413450 hasConceptScore W2076413450C158846371 @default.
- W2076413450 hasConceptScore W2076413450C185592680 @default.
- W2076413450 hasConceptScore W2076413450C188261085 @default.
- W2076413450 hasConceptScore W2076413450C2776406671 @default.
- W2076413450 hasConceptScore W2076413450C2776577112 @default.
- W2076413450 hasConceptScore W2076413450C2776694085 @default.
- W2076413450 hasConceptScore W2076413450C2778286760 @default.
- W2076413450 hasConceptScore W2076413450C2778684742 @default.
- W2076413450 hasConceptScore W2076413450C2780643987 @default.
- W2076413450 hasConceptScore W2076413450C2780662894 @default.
- W2076413450 hasConceptScore W2076413450C2781092963 @default.
- W2076413450 hasConceptScore W2076413450C55493867 @default.
- W2076413450 hasConceptScore W2076413450C71924100 @default.
- W2076413450 hasIssue "S1" @default.
- W2076413450 hasLocation W20764134501 @default.
- W2076413450 hasOpenAccess W2076413450 @default.
- W2076413450 hasPrimaryLocation W20764134501 @default.
- W2076413450 hasRelatedWork W1593464380 @default.
- W2076413450 hasRelatedWork W1983836836 @default.
- W2076413450 hasRelatedWork W2000931083 @default.
- W2076413450 hasRelatedWork W2001324871 @default.
- W2076413450 hasRelatedWork W2026989657 @default.
- W2076413450 hasRelatedWork W2264104230 @default.
- W2076413450 hasRelatedWork W2476490098 @default.
- W2076413450 hasRelatedWork W2487872961 @default.
- W2076413450 hasRelatedWork W2989504441 @default.
- W2076413450 hasRelatedWork W3030646842 @default.
- W2076413450 hasVolume "11" @default.
- W2076413450 isParatext "false" @default.
- W2076413450 isRetracted "false" @default.
- W2076413450 magId "2076413450" @default.
- W2076413450 workType "article" @default.