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• W2076422473 abstract "The increasing use of high dose rate, flattening filter free, and/or small sized field beams in SBRT presents a significant challenge and calls for new tools for dosimetric measurements. The purpose of this study is to systematically investigate a high spatial-resolution (0.2mm) and high frame-rate (50 Hz) amorphous silicon flat-panel electronic portal imaging device (EPID) for SBRT quality assurance (QA). To convert a raw EPID-measured SBRT field image into water-based dose distribution, a pixel-to-pixel response of the EPID specific to the linac is required. The response function was obtained by using a Monte Carlo simulation of the photon transport in the detector and a comprehensive calibration. After the raw image is converted into the primary photon fluence, the fluence is convolved into a water-based dose distribution of the SBRT field by using a pre-generated pencil-beam kernel. The EPID-based dosimetric measurement technique was validated using both standard and flattening filter free (FFF) photon beams of all energies a medical linear accelerator with regular fields from the original machine commissioning data and irregular fields measured using a PTW 729 ion chamber array. The technique was applied to measure the distribution for a total of 24 SBRT fields of all available photon energies (6 MV, 10 MV, 15 MV, 6 MV FFF, and 10 MV FFF). Standard square fields of 2 x 2 cm2 to 20 x 20 cm2, circular fields of 2 cm to 15 cm diameters, rectangular fields of various sizes and irregular MLC fields tested using the EPID were in good agreement with TPS calculations and ion chamber array measurements. Deliveries with different monitor units and different dose rate were also tested and the results showed good linearity. The dose rate dependence was less than 1%. Two-dimensional absolute dose maps were generated from EPID raw images using the proposed conversion method and compared with the TPS calculation for QA analysis. QA results gave an average γ-test (3 mm, 3%) passing rate of 97.1% with the passing threshold of 90%. EPID measurements were also compared with PTW Seven29 ion chamber array measurements in good agreement. Measurements using the higher detector density EPID can detect more detailed dose variations than measurements using the ion chamber array, which has 1cm spacing between adjacent detectors. The high spatial resolution and high frame rate EPID proved to be an accurate and efficient dosimetric tool for SBRT QA. Through convolution with a comprehensive EPID calibration, accurate 2D dose maps can be generated for independent dosimetric verification of SBRT treatment." @default.
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• W2076422473 date "2013-10-01" @default.
• W2076422473 modified "2023-09-27" @default.
• W2076422473 title "Meeting the Challenge of SBRT QA: Development of a High-Resolution and High-Speed Dosimetry Strategy" @default.
• W2076422473 doi "https://doi.org/10.1016/j.ijrobp.2013.06.312" @default.
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