Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076454798> ?p ?o ?g. }
- W2076454798 endingPage "240" @default.
- W2076454798 startingPage "233" @default.
- W2076454798 abstract "The effects of ajoene (a potent antithrombotic agent obtained from garlic) on the tyrosine phosphorylation status of human platelet proteins were investigated by immunoblotting-based experiments using an anti-phosphotyrosine antibody. Incubation of platelets with ajoene enhanced the phosphorylation of at least four proteins (estimated MWs 76, 80, 84 and 120 kDa), both in resting platelets and in platelets subsequently stimulated with thrombin (0.1 U/ml). This effect was both dose- and incubation-time-dependent. High concentrations of ajoene (50 microM) or long periods of incubation (10 min) led to nonselective 'hyperphosphorylation' of numerous proteins. The effects of ajoene on protein tyrosine phosphatase (PTP) activity in platelet lysates were also investigated, PTP activity was inhibited when platelets were incubated with ajoene before lysis, but not when ajoene was added to lysates of platelets which had not been pre-exposed to ajoene." @default.
- W2076454798 created "2016-06-24" @default.
- W2076454798 creator A5023060236 @default.
- W2076454798 creator A5054626649 @default.
- W2076454798 creator A5064120429 @default.
- W2076454798 date "1997-02-01" @default.
- W2076454798 modified "2023-09-27" @default.
- W2076454798 title "Inhibition by ajoene of protein tyrosine phosphatase activity in human platelets" @default.
- W2076454798 cites W1036181247 @default.
- W2076454798 cites W112257339 @default.
- W2076454798 cites W1790227735 @default.
- W2076454798 cites W1817387811 @default.
- W2076454798 cites W1964241520 @default.
- W2076454798 cites W1976474721 @default.
- W2076454798 cites W1979034912 @default.
- W2076454798 cites W1983389638 @default.
- W2076454798 cites W1987307749 @default.
- W2076454798 cites W1989305528 @default.
- W2076454798 cites W1999512126 @default.
- W2076454798 cites W2000592367 @default.
- W2076454798 cites W2001612991 @default.
- W2076454798 cites W2012514869 @default.
- W2076454798 cites W2022319113 @default.
- W2076454798 cites W2027980005 @default.
- W2076454798 cites W2029931901 @default.
- W2076454798 cites W2032618552 @default.
- W2076454798 cites W2032667632 @default.
- W2076454798 cites W2033643982 @default.
- W2076454798 cites W2036306165 @default.
- W2076454798 cites W2041231914 @default.
- W2076454798 cites W2041255507 @default.
- W2076454798 cites W2058059588 @default.
- W2076454798 cites W2059188737 @default.
- W2076454798 cites W2061099385 @default.
- W2076454798 cites W2063984250 @default.
- W2076454798 cites W2068727414 @default.
- W2076454798 cites W2072588863 @default.
- W2076454798 cites W2075466600 @default.
- W2076454798 cites W2076069294 @default.
- W2076454798 cites W2078996907 @default.
- W2076454798 cites W2085179247 @default.
- W2076454798 cites W2089069331 @default.
- W2076454798 cites W2094940251 @default.
- W2076454798 cites W2095574301 @default.
- W2076454798 cites W2096014202 @default.
- W2076454798 cites W2097065696 @default.
- W2076454798 cites W2098997742 @default.
- W2076454798 cites W2100837269 @default.
- W2076454798 cites W2155010287 @default.
- W2076454798 cites W2160421139 @default.
- W2076454798 cites W2335813458 @default.
- W2076454798 cites W2887409834 @default.
- W2076454798 doi "https://doi.org/10.1016/s0167-4838(96)00170-7" @default.
- W2076454798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9048900" @default.
- W2076454798 hasPublicationYear "1997" @default.
- W2076454798 type Work @default.
- W2076454798 sameAs 2076454798 @default.
- W2076454798 citedByCount "14" @default.
- W2076454798 countsByYear W20764547982020 @default.
- W2076454798 crossrefType "journal-article" @default.
- W2076454798 hasAuthorship W2076454798A5023060236 @default.
- W2076454798 hasAuthorship W2076454798A5054626649 @default.
- W2076454798 hasAuthorship W2076454798A5064120429 @default.
- W2076454798 hasConcept C11960822 @default.
- W2076454798 hasConcept C178666793 @default.
- W2076454798 hasConcept C185592680 @default.
- W2076454798 hasConcept C203014093 @default.
- W2076454798 hasConcept C25642318 @default.
- W2076454798 hasConcept C2776165026 @default.
- W2076454798 hasConcept C2777292125 @default.
- W2076454798 hasConcept C2777553839 @default.
- W2076454798 hasConcept C2778198054 @default.
- W2076454798 hasConcept C55493867 @default.
- W2076454798 hasConcept C85528070 @default.
- W2076454798 hasConcept C86803240 @default.
- W2076454798 hasConcept C89560881 @default.
- W2076454798 hasConceptScore W2076454798C11960822 @default.
- W2076454798 hasConceptScore W2076454798C178666793 @default.
- W2076454798 hasConceptScore W2076454798C185592680 @default.
- W2076454798 hasConceptScore W2076454798C203014093 @default.
- W2076454798 hasConceptScore W2076454798C25642318 @default.
- W2076454798 hasConceptScore W2076454798C2776165026 @default.
- W2076454798 hasConceptScore W2076454798C2777292125 @default.
- W2076454798 hasConceptScore W2076454798C2777553839 @default.
- W2076454798 hasConceptScore W2076454798C2778198054 @default.
- W2076454798 hasConceptScore W2076454798C55493867 @default.
- W2076454798 hasConceptScore W2076454798C85528070 @default.
- W2076454798 hasConceptScore W2076454798C86803240 @default.
- W2076454798 hasConceptScore W2076454798C89560881 @default.
- W2076454798 hasIssue "2" @default.
- W2076454798 hasLocation W20764547981 @default.
- W2076454798 hasLocation W20764547982 @default.
- W2076454798 hasOpenAccess W2076454798 @default.
- W2076454798 hasPrimaryLocation W20764547981 @default.
- W2076454798 hasRelatedWork W1505417279 @default.
- W2076454798 hasRelatedWork W1965518306 @default.
- W2076454798 hasRelatedWork W1986604108 @default.
- W2076454798 hasRelatedWork W2000149489 @default.