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- W2076457653 abstract "A review of the serologic data on 540 proven cases of chronic pulmonary histoplasmosis and 45 proven cases of chronic pulmonary blastomycosis revealed that 92 per cent of the histoplasmosis cases and 72 per cent of the blastomycosis cases had a positive CF test to one or more of the three antigens employed. Of the histoplasmosis cases, 90 per cent had a positive CF test for histoplasmosis. Among the 45 blastomycosis cases, only 36 per cent had a positive CF test for blastomycosis. When the homologous antigens were used, a titer of 1: 32 or greater was recorded for 68 per cent of the histoplasmosis cases, while only 9 per cent of the blastomycosis cases had titers of this magnitude. Ten per cent of the histoplasmosis cases and 64 per cent of the blastomycosis cases had negative tests. Cross reactions of CF antibodies between the antigens of H. capsulatum and B. dermatitidis present problems in diagnosis. The titers were greater for the homologous antigens for 84 per cent of the histoplasmosis cases and only 22 per cent of the blastomycosis cases. The best solution to the problem is to perform the CF test with the antigens of both fungi and also perform the test upon serial serum specimens." @default.
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- W2076457653 date "1967-05-01" @default.
- W2076457653 modified "2023-09-25" @default.
- W2076457653 title "The complement fixation antibody test in the diagnosis of chronic pulmonary histoplasmosis and blastomycosis" @default.
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- W2076457653 doi "https://doi.org/10.1016/0021-9681(67)90058-6" @default.
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