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- W2076457657 endingPage "834" @default.
- W2076457657 startingPage "815" @default.
- W2076457657 abstract "Midbrain dopamine neurons are well known for their strong responses to rewards and their critical role in positive motivation. It has become increasingly clear, however, that dopamine neurons also transmit signals related to salient but nonrewarding experiences such as aversive and alerting events. Here we review recent advances in understanding the reward and nonreward functions of dopamine. Based on this data, we propose that dopamine neurons come in multiple types that are connected with distinct brain networks and have distinct roles in motivational control. Some dopamine neurons encode motivational value, supporting brain networks for seeking, evaluation, and value learning. Others encode motivational salience, supporting brain networks for orienting, cognition, and general motivation. Both types of dopamine neurons are augmented by an alerting signal involved in rapid detection of potentially important sensory cues. We hypothesize that these dopaminergic pathways for value, salience, and alerting cooperate to support adaptive behavior." @default.
- W2076457657 created "2016-06-24" @default.
- W2076457657 creator A5009259014 @default.
- W2076457657 creator A5009985808 @default.
- W2076457657 creator A5018605011 @default.
- W2076457657 date "2010-12-01" @default.
- W2076457657 modified "2023-10-14" @default.
- W2076457657 title "Dopamine in Motivational Control: Rewarding, Aversive, and Alerting" @default.
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