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- W2076463185 endingPage "446" @default.
- W2076463185 startingPage "441" @default.
- W2076463185 abstract "Chromosome ends, or telomeres, are formed by a special chromatin structure that protects them from recombination and degradation, thus preventing end-to-end chromosome fusions and other chromosomal aberrations. The functionality of telomeres, and that of the cellular activity that synthesizes them, telomerase, has been shown to impact on both cancer and aging, as well as on the organismal sensitivity to ionizing radiation. This review focuses on the analysis of different mouse models for proteins that are important for telomere function, which have highlighted the importance of telomeres and telomerase for cancer and aging." @default.
- W2076463185 created "2016-06-24" @default.
- W2076463185 creator A5085977927 @default.
- W2076463185 date "2003-09-01" @default.
- W2076463185 modified "2023-10-03" @default.
- W2076463185 title "Mammalian telomeres and telomerase: why they matter for cancer and aging" @default.
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- W2076463185 doi "https://doi.org/10.1078/0171-9335-00335" @default.
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- W2076463185 hasPublicationYear "2003" @default.
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