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• W2076474920 abstract "No AccessJournal of UrologyUrolithiasis1 Oct 2011Association Between Body Mass Index and Urolithiasis in Children Steve S. Kim, Xianqun Luan, Douglas A. Canning, J. Richard Landis, and Ron Keren Steve S. KimSteve S. Kim Division of Pediatric Urology, Children's Hospital Los Angeles, Los Angeles, California More articles by this author , Xianqun LuanXianqun Luan Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania More articles by this author , Douglas A. CanningDouglas A. Canning Division of Pediatric Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania More articles by this author , J. Richard LandisJ. Richard Landis Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania Financial interest and/or other relationship with Bristol-Myers Squibb. More articles by this author , and Ron KerenRon Keren Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Financial interest and/or other relationship with Tengion. More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.04.009AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: The prevalence of obesity and urolithiasis in children has increased with time. We evaluated the relationship between body mass and urolithiasis in children. Materials and Methods: We performed a matched case-control study in a network of 30 primary care pediatric practices. Cases included subjects with ICD-9 codes for urolithiasis and controls were matched on age, duration of observation before the index date and clinical practice. Age and sex specific body mass index z scores at the time of the stone episode were calculated. Continuous body mass index z scores and clinical weight categories were evaluated with covariates, including race, ethnicity, gender and payer status. The OR and 95% CI were calculated using multivariate conditional logistic regression. Results: We identified 110 cases and 396 matched controls, of whom 1.9% and 4.3% were overweight, and 3.7% and 4.5% were obese, respectively. On multivariate conditional logistic regression analysis the continuous body mass index z score (OR 0.84, 95% CI 0.63–1.12, p = 0.18), overweight status (OR 0.13, 95% CI 0.01–1.18) and obese status (OR 0.18, 95% CI 0.02–1.40) were not associated with urolithiasis. However, black race (OR 0.35, 95% CI 0.15–0.85) and Medicaid payer status (OR 0.47, 95% CI 0.24–0.93) were associated with a significant decrease in the odds of urolithiasis. Conclusions: High body mass was not associated with urolithiasis in our primary care pediatric practice network. However, black race and Medicaid payer status were associated with decreased odds of urolithiasis. References 1 : Obesity, weight gain, and the risk of kidney stones. JAMA2005; 293: 455. Google Scholar 2 : The association of increasing body mass index and kidney stone disease. J Urol2010; 183: 571. Link, Google Scholar 3 : Obesity: Halting the Epidemic by Making Health Easier. At a Glance 2011. Centers for Disease Control and Prevention http://www.cdc.gov/chronicdisease/resources/publications/AAG/obesity.htm. Accessed May 25, 2010. Google Scholar 4 : Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Intl2003; 63: 1817. Google Scholar 5 : The role of overweight and obesity in calcium oxalate stone formation. Obesity Res2004; 12: 106. Google Scholar 6 : Body size and 24-hour urine composition. Am J Kid Dis2006; 48: 905. Google Scholar 7 : Prevalence of high body mass index in US children and adolescents, 2007–2008. JAMA2010; 303: 242. 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Link, Google Scholar 15 : Influence of body mass index on quantitative 24-hour urine chemistry studies in children with nephrolithiasis. J Urol2009; 182: 1142. Link, Google Scholar 16 : Pediatric urolithiasis—does body mass index influence stone presentation and treatment?. J Urol2010; 184: 1810. Link, Google Scholar 17 : Urinary lithiasis in the black population: an epidemiological study and review of the literature. J Urol1987; 138: 14. Link, Google Scholar 18 : Demographic and geographic variability of kidney stones in the United States. Intl Soc Nephrol1994; 46: 893. Google Scholar 19 : Sex prevalence of pediatric kidney stone disease in the United States: an epidemiologic investigation. Urology2009; 74: 104. Google Scholar 20 : Changes in gender distribution of urinary stone disease. Urology2010; 75: 543. Google Scholar 21 : Changing gender prevalence of stone disease. J Urol2007; 177: 979. Link, Google Scholar © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byAlfandary H, Haskin O, Davidovits M, Pleniceanu O, Leiba A and Dagan A (2018) Increasing Prevalence of Nephrolithiasis in Association with Increased Body Mass Index in Children: A Population Based StudyJournal of Urology, VOL. 199, NO. 4, (1044-1049), Online publication date: 1-Apr-2018.Bandari J, Dangle P, Lyon T, Lee A, Schneck F, Cannon G, Stephany H and Ost M (2018) 24-Hour Urinary Parameters in Overweight and Obese Children with UrolithiasisJournal of Urology, VOL. 196, NO. 2, (526-530), Online publication date: 1-Aug-2016. Volume 186Issue 4SOctober 2011Page: 1734-1739 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.KeywordsurolithiasisAfrican AmericansMedicaidkidneyobesityAcknowledgmentsDr. Robert Grundmeier, Jonathan Crossette and Jason Ramos, Children's Hospital of Philadelphia Clinical Reporting Unit, Center for BioMedical Informatics, and Katie Tremont assisted with data collection. Dr. Harold Feldman provided mentorship.MetricsAuthor Information Steve S. Kim Division of Pediatric Urology, Children's Hospital Los Angeles, Los Angeles, California More articles by this author Xianqun Luan Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania More articles by this author Douglas A. Canning Division of Pediatric Urology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania More articles by this author J. Richard Landis Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania Financial interest and/or other relationship with Bristol-Myers Squibb. More articles by this author Ron Keren Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania Financial interest and/or other relationship with Tengion. More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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