FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076479783> ?p ?o ?g. }

• W2076479783 abstract "Glutamine (Gln) participates in the so-called brain glutamine-glutamate cycle and therefore it is likely to influence brain excitability. Here we investigated, in weaned well-nourished and early-malnourished rats, the effects of previous Gln oral supplementation, during the brain development period, on cortical spreading depression (CSD), an excitability-related brain phenomenon.Male Wistar (W) suckling rat pups, well-nourished (litters with 6 pups) and malnourished (M) during lactation (by increasing the litters to 12 pups), received Gln (500 mg/kg/day) by gavage during postnatal days 7 to 27. At 30-40 days of life, they were submitted to a cortical spreading depression (CSD) recording session during 4 h, on 2 cortical parietal points of the right hemisphere. CSD velocity propagation was calculated from the time required for a CSD wave to cross the inter-electrode distance.In both nutritional condition, Gln rats presented higher (p<0.05) CSD propagation velocities (W-Gln, 4.22+/-0.23; M-Gln, 4.51+/-0.27 mm/min), as compared to water-treated controls (W-Wa, 3.77+/-0.21; M-Wa, 4.15+/-0.18 mm/min). This water control group did not differ from a naive control group that was not submitted to the gavage procedure. A fourth group, treated with a placebo amino acid (glycine), also displayed CSD velocities in the control range.The results indicate that Gln supplementation during brain development facilitates cortical spreading depression propagation, as judged by the higher CSD velocities, and this effect is not abolished by malnutrition. Data support the idea of Gln-related changes in brain excitability, during neural development." @default.
• W2076479783 created "2016-06-24" @default.
• W2076479783 creator A5011125723 @default.
• W2076479783 creator A5036534960 @default.
• W2076479783 creator A5054344240 @default.
• W2076479783 creator A5064375158 @default.
• W2076479783 creator A5072160041 @default.
• W2076479783 creator A5074425694 @default.
• W2076479783 date "2009-07-01" @default.
• W2076479783 modified "2023-10-16" @default.
• W2076479783 title "l-Glutamine supplementation during the lactation period facilitates cortical spreading depression in well-nourished and early-malnourished rats" @default.
• W2076479783 cites W1484355820 @default.
• W2076479783 cites W170852266 @default.
• W2076479783 cites W1930183105 @default.
• W2076479783 cites W1991381807 @default.
• W2076479783 cites W1992521533 @default.
• W2076479783 cites W1995005517 @default.
• W2076479783 cites W1998479228 @default.
• W2076479783 cites W1999838834 @default.
• W2076479783 cites W2004296414 @default.
• W2076479783 cites W2009889686 @default.
• W2076479783 cites W2010024335 @default.
• W2076479783 cites W2017543176 @default.
• W2076479783 cites W2018649485 @default.
• W2076479783 cites W2021394489 @default.
• W2076479783 cites W2026526415 @default.
• W2076479783 cites W2029624481 @default.
• W2076479783 cites W2032122752 @default.
• W2076479783 cites W2032199741 @default.
• W2076479783 cites W2044107476 @default.
• W2076479783 cites W2046704813 @default.
• W2076479783 cites W2054341520 @default.
• W2076479783 cites W2058701143 @default.
• W2076479783 cites W2060771620 @default.
• W2076479783 cites W2065441026 @default.
• W2076479783 cites W2065663423 @default.
• W2076479783 cites W2066238766 @default.
• W2076479783 cites W2074216751 @default.
• W2076479783 cites W2075166773 @default.
• W2076479783 cites W2078474076 @default.
• W2076479783 cites W2085503685 @default.
• W2076479783 cites W2085971070 @default.
• W2076479783 cites W2114017269 @default.
• W2076479783 cites W2135273834 @default.
• W2076479783 cites W2139190393 @default.
• W2076479783 cites W2140157348 @default.
• W2076479783 cites W2144950446 @default.
• W2076479783 cites W2150200613 @default.
• W2076479783 cites W2152278909 @default.
• W2076479783 cites W2163666049 @default.
• W2076479783 cites W2217637761 @default.
• W2076479783 cites W2243408637 @default.
• W2076479783 cites W2318926611 @default.
• W2076479783 cites W2474651723 @default.
• W2076479783 cites W63959852 @default.
• W2076479783 doi "https://doi.org/10.1016/j.lfs.2009.05.017" @default.
• W2076479783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19508874" @default.
• W2076479783 hasPublicationYear "2009" @default.
• W2076479783 type Work @default.
• W2076479783 sameAs 2076479783 @default.
• W2076479783 citedByCount "15" @default.
• W2076479783 countsByYear W20764797832012 @default.
• W2076479783 countsByYear W20764797832014 @default.
• W2076479783 countsByYear W20764797832015 @default.
• W2076479783 countsByYear W20764797832016 @default.
• W2076479783 countsByYear W20764797832017 @default.
• W2076479783 countsByYear W20764797832019 @default.
• W2076479783 crossrefType "journal-article" @default.
• W2076479783 hasAuthorship W2076479783A5011125723 @default.
• W2076479783 hasAuthorship W2076479783A5036534960 @default.
• W2076479783 hasAuthorship W2076479783A5054344240 @default.
• W2076479783 hasAuthorship W2076479783A5064375158 @default.
• W2076479783 hasAuthorship W2076479783A5072160041 @default.
• W2076479783 hasAuthorship W2076479783A5074425694 @default.
• W2076479783 hasBestOaLocation W20764797831 @default.
• W2076479783 hasConcept C121332964 @default.
• W2076479783 hasConcept C122356138 @default.
• W2076479783 hasConcept C126322002 @default.
• W2076479783 hasConcept C134018914 @default.
• W2076479783 hasConcept C139719470 @default.
• W2076479783 hasConcept C162324750 @default.
• W2076479783 hasConcept C169760540 @default.
• W2076479783 hasConcept C170493617 @default.
• W2076479783 hasConcept C24890656 @default.
• W2076479783 hasConcept C2776659692 @default.
• W2076479783 hasConcept C2776867660 @default.
• W2076479783 hasConcept C2778541695 @default.
• W2076479783 hasConcept C2779234561 @default.
• W2076479783 hasConcept C2779349466 @default.
• W2076479783 hasConcept C2781291010 @default.
• W2076479783 hasConcept C2984223407 @default.
• W2076479783 hasConcept C42407357 @default.
• W2076479783 hasConcept C515207424 @default.
• W2076479783 hasConcept C54355233 @default.
• W2076479783 hasConcept C551997983 @default.
• W2076479783 hasConcept C55493867 @default.
• W2076479783 hasConcept C61174792 @default.
• W2076479783 hasConcept C71924100 @default.
• W2076479783 hasConcept C86803240 @default.
• W2076479783 hasConceptScore W2076479783C121332964 @default.

• next