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• W2076504751 abstract "Molecules associated with dead or dying cells can be detected by receptors on macrophages and dendritic cells. Signals from these receptors impact myeloid cell function and play a role in determining whether death is silent or proinflammatory, tolerogenic or immunogenic. Prominent among myeloid receptors detecting dead cells are C-type lectin receptors (CLRs). Signals from these receptors variably induce endocytosis of cell corpses, corpse degradation, retrieval of dead cell-associated antigens and/or modulation of immune responses. The sensing of tissue damage by myeloid CLRs complements detection of pathogens in immunity and represents an ancient response aimed at restoring tissue homeostasis." @default.
• W2076504751 created "2016-06-24" @default.
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• W2076504751 date "2013-02-01" @default.
• W2076504751 modified "2023-10-18" @default.
• W2076504751 title "Sensing of cell death by myeloid C-type lectin receptors" @default.
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• W2076504751 doi "https://doi.org/10.1016/j.coi.2012.12.007" @default.
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