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- W2076510618 abstract "A 4-week-old male infant who developed blisters on the face, hands and buttocks immediately after birth was diagnosed as suffering from generalized epidermolysis bullosa (EB) simplex (Köbner). At 6 months of age, centrifugally expanding erythema circinatum suddenly appeared on the trunk and limbs. Blood tests showed transient elevation of liver enzymes. An intercurrent illness such as a bacterial or viral infection, or an adverse reaction to a drug was suspected, but no supportive evidence was obtained. The circinate or arciform pattern of the eruption, and the ultrastructural findings of basal cell cytolysis and some tonofilament aggregation suggested a possible diagnosis of epidermolysis bullosa herpetiformis (Dowling-Meara) [DM-EB]. However, the predominant feature of this child's dermatosis was erythema circinatum, with a small number of blisters limited to the areas affected by erythema. The erythema resolved spontaneously after 8 months. Round or whisk-like clumping of tonofilaments, a typical finding in DM-EB, was not demonstrated on electron microscopy. These observations were not consistent with classical DM-EB, and we consider that this case is an unusual form of EB simplex showing transient erythema circinatum." @default.
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- W2076510618 date "2006-07-29" @default.
- W2076510618 modified "2023-10-16" @default.
- W2076510618 title "Epidermolysis bullosa simplex with transient erythema circinatum" @default.
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- W2076510618 doi "https://doi.org/10.1111/j.1365-2133.1994.tb08563.x" @default.
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