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• W2076525366 abstract "In the nematode model organisms Caenorhabditis elegans and Pristionchus pacificus, a new class of natural products based on modular assembly of primary-metabolism-derived building blocks control organismal development and behavior. We report identification and biological activities of the first pentamodular metabolite, pasa#9, and the 8-oxoadenine-containing npar#3 from P. pacificus. These structures suggest co-option of nucleoside and tryptophan metabolic pathways for the biosynthesis of endogenous metabolite libraries that transcend the dichotomy between “primary” and “secondary” metabolism." @default.
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• W2076525366 date "2015-03-18" @default.
• W2076525366 modified "2023-10-07" @default.
• W2076525366 title "Nematode Signaling Molecules Derived from Multimodular Assembly of Primary Metabolic Building Blocks" @default.
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• W2076525366 doi "https://doi.org/10.1021/acs.orglett.5b00329" @default.
• W2076525366 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4878434" @default.
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