Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076571490> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2076571490 endingPage "1064" @default.
- W2076571490 startingPage "1062" @default.
- W2076571490 abstract "Transcription-repair coupling factors (TRCFs) are SF2 ATPases that couple transcription to DNA-damage repair by recognizing and removing RNA polymerase-elongation complexes stalled at DNA lesions and recruiting the nucleotide excision-repair machinery to the damaged sites. As a first step towards understanding the TRCF mechanism, the 130 kDa Escherichia coli TRCF (the product of the mfd gene) has been overexpressed, purified and crystallized using an unusual precipitant, pentaerythritol ethoxylate. Initial phases were obtained using single-wavelength anomalous dispersion with a highly redundant 4 A resolution data set collected from selenomethionyl-substituted crystals and dramatically improved by density modification and phase extension to 3.2 A resolution. Model building and refinement, which are in progress, will provide insight into transcription-coupled DNA-repair pathways, as this represents the first TRCF to be crystallized to date." @default.
- W2076571490 created "2016-06-24" @default.
- W2076571490 creator A5069772661 @default.
- W2076571490 creator A5078511607 @default.
- W2076571490 date "2005-11-24" @default.
- W2076571490 modified "2023-09-26" @default.
- W2076571490 title "Crystallization and preliminary structure determination of<i>Escherichia coli</i>Mfd, the transcription-repair coupling factor" @default.
- W2076571490 cites W1539796472 @default.
- W2076571490 cites W2004328215 @default.
- W2076571490 cites W2042639517 @default.
- W2076571490 cites W2049353359 @default.
- W2076571490 cites W2079039953 @default.
- W2076571490 cites W2101446086 @default.
- W2076571490 cites W2168044649 @default.
- W2076571490 doi "https://doi.org/10.1107/s1744309105035876" @default.
- W2076571490 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1978150" @default.
- W2076571490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16511235" @default.
- W2076571490 hasPublicationYear "2005" @default.
- W2076571490 type Work @default.
- W2076571490 sameAs 2076571490 @default.
- W2076571490 citedByCount "20" @default.
- W2076571490 countsByYear W20765714902012 @default.
- W2076571490 countsByYear W20765714902013 @default.
- W2076571490 countsByYear W20765714902015 @default.
- W2076571490 countsByYear W20765714902018 @default.
- W2076571490 countsByYear W20765714902019 @default.
- W2076571490 countsByYear W20765714902020 @default.
- W2076571490 countsByYear W20765714902021 @default.
- W2076571490 countsByYear W20765714902023 @default.
- W2076571490 crossrefType "journal-article" @default.
- W2076571490 hasAuthorship W2076571490A5069772661 @default.
- W2076571490 hasAuthorship W2076571490A5078511607 @default.
- W2076571490 hasBestOaLocation W20765714902 @default.
- W2076571490 hasConcept C104317684 @default.
- W2076571490 hasConcept C104451858 @default.
- W2076571490 hasConcept C12554922 @default.
- W2076571490 hasConcept C134935766 @default.
- W2076571490 hasConcept C138885662 @default.
- W2076571490 hasConcept C153911025 @default.
- W2076571490 hasConcept C178790620 @default.
- W2076571490 hasConcept C179926584 @default.
- W2076571490 hasConcept C185592680 @default.
- W2076571490 hasConcept C205474432 @default.
- W2076571490 hasConcept C2776449523 @default.
- W2076571490 hasConcept C2778420591 @default.
- W2076571490 hasConcept C41895202 @default.
- W2076571490 hasConcept C54355233 @default.
- W2076571490 hasConcept C547475151 @default.
- W2076571490 hasConcept C552990157 @default.
- W2076571490 hasConcept C86803240 @default.
- W2076571490 hasConcept C95444343 @default.
- W2076571490 hasConceptScore W2076571490C104317684 @default.
- W2076571490 hasConceptScore W2076571490C104451858 @default.
- W2076571490 hasConceptScore W2076571490C12554922 @default.
- W2076571490 hasConceptScore W2076571490C134935766 @default.
- W2076571490 hasConceptScore W2076571490C138885662 @default.
- W2076571490 hasConceptScore W2076571490C153911025 @default.
- W2076571490 hasConceptScore W2076571490C178790620 @default.
- W2076571490 hasConceptScore W2076571490C179926584 @default.
- W2076571490 hasConceptScore W2076571490C185592680 @default.
- W2076571490 hasConceptScore W2076571490C205474432 @default.
- W2076571490 hasConceptScore W2076571490C2776449523 @default.
- W2076571490 hasConceptScore W2076571490C2778420591 @default.
- W2076571490 hasConceptScore W2076571490C41895202 @default.
- W2076571490 hasConceptScore W2076571490C54355233 @default.
- W2076571490 hasConceptScore W2076571490C547475151 @default.
- W2076571490 hasConceptScore W2076571490C552990157 @default.
- W2076571490 hasConceptScore W2076571490C86803240 @default.
- W2076571490 hasConceptScore W2076571490C95444343 @default.
- W2076571490 hasIssue "12" @default.
- W2076571490 hasLocation W20765714901 @default.
- W2076571490 hasLocation W20765714902 @default.
- W2076571490 hasLocation W20765714903 @default.
- W2076571490 hasLocation W20765714904 @default.
- W2076571490 hasOpenAccess W2076571490 @default.
- W2076571490 hasPrimaryLocation W20765714901 @default.
- W2076571490 hasRelatedWork W1541631361 @default.
- W2076571490 hasRelatedWork W1552376471 @default.
- W2076571490 hasRelatedWork W2005762860 @default.
- W2076571490 hasRelatedWork W2048565695 @default.
- W2076571490 hasRelatedWork W2068279725 @default.
- W2076571490 hasRelatedWork W2087091691 @default.
- W2076571490 hasRelatedWork W2104864650 @default.
- W2076571490 hasRelatedWork W2142203322 @default.
- W2076571490 hasRelatedWork W2159453189 @default.
- W2076571490 hasRelatedWork W2549157240 @default.
- W2076571490 hasVolume "61" @default.
- W2076571490 isParatext "false" @default.
- W2076571490 isRetracted "false" @default.
- W2076571490 magId "2076571490" @default.
- W2076571490 workType "article" @default.