FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076575281> ?p ?o ?g. }

• W2076575281 endingPage "226" @default.
• W2076575281 startingPage "212" @default.
• W2076575281 abstract "Homeobox genes are an evolutionarily conserved class of transcription factors that are key regulators of developmental processes such as regional specification, patterning, migration and differentiation. In both mouse and humans, the developing forebrain is marked by distinct boundaries of homeobox gene expression at different developmental time points. These genes regulate the patterning of the forebrain along the dorsal/ventral and rostral/caudal axes and are also essential for the differentiation of specific neuronal subtypes. Inhibitory interneurons that arise from the ganglionic eminences and migrate tangentially to the neocortex and hippocampus are dramatically affected by mutations in several homeobox genes. In this review, we discuss the identification, expression patterns, loss- and/or gain-of-function models, and confirmed transcriptional targets for a set of homeobox genes required for the correct development of the forebrain in the mouse. In humans, mutations of homeobox genes expressed in the forebrain have been shown to result in mental retardation, epilepsy or movement disorders. The number of homeobox genes currently linked to human nervous system disease is surprisingly low, perhaps reflecting the essential functions of these genes throughout embryogenesis or the degree of functional redundancy during central nervous system development." @default.
• W2076575281 created "2016-06-24" @default.
• W2076575281 creator A5005668372 @default.
• W2076575281 creator A5077859335 @default.
• W2076575281 date "2008-01-31" @default.
• W2076575281 modified "2023-10-12" @default.
• W2076575281 title "Homeobox genes in vertebrate forebrain development and disease" @default.
• W2076575281 cites W1520825673 @default.
• W2076575281 cites W1537398925 @default.
• W2076575281 cites W1544789027 @default.
• W2076575281 cites W1580878352 @default.
• W2076575281 cites W1618939505 @default.
• W2076575281 cites W1715204582 @default.
• W2076575281 cites W1844026860 @default.
• W2076575281 cites W1857568828 @default.
• W2076575281 cites W1895052039 @default.
• W2076575281 cites W1933799138 @default.
• W2076575281 cites W1947231608 @default.
• W2076575281 cites W1964745963 @default.
• W2076575281 cites W1964761197 @default.
• W2076575281 cites W1967445973 @default.
• W2076575281 cites W1969890750 @default.
• W2076575281 cites W1970681659 @default.
• W2076575281 cites W1971305731 @default.
• W2076575281 cites W1971825511 @default.
• W2076575281 cites W1974792476 @default.
• W2076575281 cites W1977360479 @default.
• W2076575281 cites W1978388786 @default.
• W2076575281 cites W1981544525 @default.
• W2076575281 cites W1982662107 @default.
• W2076575281 cites W1982763652 @default.
• W2076575281 cites W1984112963 @default.
• W2076575281 cites W1984122545 @default.
• W2076575281 cites W1985020768 @default.
• W2076575281 cites W1985348819 @default.
• W2076575281 cites W1989564089 @default.
• W2076575281 cites W1992383169 @default.
• W2076575281 cites W1998167315 @default.
• W2076575281 cites W2001560369 @default.
• W2076575281 cites W2001657520 @default.
• W2076575281 cites W2001954678 @default.
• W2076575281 cites W2002793039 @default.
• W2076575281 cites W2003774068 @default.
• W2076575281 cites W2004257326 @default.
• W2076575281 cites W2005402594 @default.
• W2076575281 cites W2006551649 @default.
• W2076575281 cites W2007034511 @default.
• W2076575281 cites W2009580795 @default.
• W2076575281 cites W2015038624 @default.
• W2076575281 cites W2017400430 @default.
• W2076575281 cites W2017954097 @default.
• W2076575281 cites W2018947009 @default.
• W2076575281 cites W2020732030 @default.
• W2076575281 cites W2023195093 @default.
• W2076575281 cites W2027945762 @default.
• W2076575281 cites W2029676157 @default.
• W2076575281 cites W2031224620 @default.
• W2076575281 cites W2031482377 @default.
• W2076575281 cites W2031842064 @default.
• W2076575281 cites W2034464093 @default.
• W2076575281 cites W2035078318 @default.
• W2076575281 cites W2035378222 @default.
• W2076575281 cites W2036334886 @default.
• W2076575281 cites W2037344427 @default.
• W2076575281 cites W2037923901 @default.
• W2076575281 cites W2041170795 @default.
• W2076575281 cites W2045533959 @default.
• W2076575281 cites W2047493187 @default.
• W2076575281 cites W2047498240 @default.
• W2076575281 cites W2052065200 @default.
• W2076575281 cites W2055421069 @default.
• W2076575281 cites W2056328047 @default.
• W2076575281 cites W2056577696 @default.
• W2076575281 cites W2057113688 @default.
• W2076575281 cites W2057158421 @default.
• W2076575281 cites W2059086372 @default.
• W2076575281 cites W2060612598 @default.
• W2076575281 cites W2061230077 @default.
• W2076575281 cites W2064624464 @default.
• W2076575281 cites W2064792767 @default.
• W2076575281 cites W2065112950 @default.
• W2076575281 cites W2071540975 @default.
• W2076575281 cites W2072128770 @default.
• W2076575281 cites W2074887037 @default.
• W2076575281 cites W2077397273 @default.
• W2076575281 cites W2077423081 @default.
• W2076575281 cites W2078590305 @default.
• W2076575281 cites W2079816742 @default.
• W2076575281 cites W2080056868 @default.
• W2076575281 cites W2080598828 @default.
• W2076575281 cites W2082490413 @default.
• W2076575281 cites W2083404062 @default.
• W2076575281 cites W2086250515 @default.
• W2076575281 cites W2087716957 @default.
• W2076575281 cites W2088176415 @default.
• W2076575281 cites W2089129747 @default.
• W2076575281 cites W2089524779 @default.
• W2076575281 cites W2094145003 @default.

• next