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- W2076582678 abstract "The present work was carried out to study the effect of β-carotene (β) or β-carotene encapsulated in liposomes (L+β) on tumoricidal activity of human monocytes (HM). Tumoricidal activity of HM was measured by using 125I-iododeoxyuridine labeled C83-2C human melanoma cells. Maximum tumoricidal activity of HM was obtained after in vitro incubation with 10−7M of β or L+β. And L+β induced higher tumoricidal activity of HM than that of β. Higher tumoricidal activity of HM (20.4%) was induced by in vitro incubation with L+β for 3 hr and it reached a maximum at 24 hr-incubation. Tumoricidal activity rendered by incubation in vitro with L+β gradually decreased and fell to half of maximum activity following further incubation with medium only for 72 hr. These results suggest that β induces HM to become tumoricidal and L+β may further enhance the effect of β on tumoricidal activity of HM." @default.
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- W2076582678 date "1990-08-01" @default.
- W2076582678 modified "2023-10-16" @default.
- W2076582678 title "In vitro activation of tumoricidal properties of human monocytes by β-carotene encapsulated in liposomes" @default.
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- W2076582678 doi "https://doi.org/10.1016/s0271-5317(05)80049-1" @default.
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