FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076584438> ?p ?o ?g. }

• W2076584438 endingPage "933" @default.
• W2076584438 startingPage "933" @default.
• W2076584438 abstract "Mussels possess the ability to attach to virtually any type of inorganic and organic surfaces due to the existence of phenylalamine and lysine amino acids. Inspired by the property of mussels, polydopamine has been used for modifying bioinert materials, such as metals, semiconductors and plastics to improve their surface hydrophilicity. However, there are no reports about the effect of a polydopamine modification on apatite mineralization and the biological response of bioactive ceramics (not bioinert materials) for bone regeneration applications. Akermanite bioceramics (AKT, Ca2MgSi2O7) are a typical bioactive material with osteostimulation properties for bone tissue regeneration. The aim of this study is to systematically investigate the effect of a polydopamine modification on the physicochemical and biological properties of AKT bioceramics, including attachment, proliferation, ALP activity and bone-related gene expression of tissue cells. The results show that a self-assembled polydopamine layer on the surface of AKT bioceramics was formed by incubating AKT bioceramics in a dopamine/Tris-HCl solution. Polydopamine-modified AKT (PDB-AKT) bioceramics showed significantly improved surface roughness, hydrophilicity and apatite-mineralization ability compared to AKT bioceramics. In addition, the polydopamine modification distinctively enhanced the attachment, proliferation, alkaline phosphate activity and bone-related gene expression of MC3T3 cells on AKT bioceramics. The possible reason for the improved cytocompatibility may be related to the improved surface roughness and apatite mineralization as well as the ionic environment at an early stage of cell culture. Our results suggest that the polydopamine modification is a viable method to further improve the apatite mineralization and biological response of bioactive ceramics for better bone regeneration applications, indicating that the polydopamine modification is a universal method to enhance the bioactivity for both bioinert and bioactive materials." @default.
• W2076584438 created "2016-06-24" @default.
• W2076584438 creator A5001153538 @default.
• W2076584438 creator A5004771945 @default.
• W2076584438 creator A5062987221 @default.
• W2076584438 creator A5072012950 @default.
• W2076584438 creator A5089559746 @default.
• W2076584438 date "2013-01-01" @default.
• W2076584438 modified "2023-10-07" @default.
• W2076584438 title "Mussel-inspired bioactive ceramics with improved bioactivity, cell proliferation, differentiation and bone-related gene expression of MC3T3 cells" @default.
• W2076584438 cites W1965721927 @default.
• W2076584438 cites W1974825501 @default.
• W2076584438 cites W1977740836 @default.
• W2076584438 cites W1981386795 @default.
• W2076584438 cites W1989322323 @default.
• W2076584438 cites W2006167320 @default.
• W2076584438 cites W2007566603 @default.
• W2076584438 cites W2010907441 @default.
• W2076584438 cites W2016814255 @default.
• W2076584438 cites W2017836705 @default.
• W2076584438 cites W2019047966 @default.
• W2076584438 cites W2019821895 @default.
• W2076584438 cites W2027521830 @default.
• W2076584438 cites W2034351768 @default.
• W2076584438 cites W2037860377 @default.
• W2076584438 cites W2043197511 @default.
• W2076584438 cites W2043310171 @default.
• W2076584438 cites W2044316388 @default.
• W2076584438 cites W2053127337 @default.
• W2076584438 cites W2063261010 @default.
• W2076584438 cites W2066520683 @default.
• W2076584438 cites W2078002498 @default.
• W2076584438 cites W2078797075 @default.
• W2076584438 cites W2078957576 @default.
• W2076584438 cites W2078971853 @default.
• W2076584438 cites W2084877126 @default.
• W2076584438 cites W2086699454 @default.
• W2076584438 cites W2086719714 @default.
• W2076584438 cites W2087166333 @default.
• W2076584438 cites W2091577279 @default.
• W2076584438 cites W2092858957 @default.
• W2076584438 cites W2103511109 @default.
• W2076584438 cites W2107310361 @default.
• W2076584438 cites W2111415695 @default.
• W2076584438 cites W2111577938 @default.
• W2076584438 cites W2114200005 @default.
• W2076584438 cites W2116689814 @default.
• W2076584438 cites W2154577831 @default.
• W2076584438 cites W2156598924 @default.
• W2076584438 cites W2169575300 @default.
• W2076584438 doi "https://doi.org/10.1039/c3bm60028a" @default.
• W2076584438 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32481962" @default.
• W2076584438 hasPublicationYear "2013" @default.
• W2076584438 type Work @default.
• W2076584438 sameAs 2076584438 @default.
• W2076584438 citedByCount "33" @default.
• W2076584438 countsByYear W20765844382014 @default.
• W2076584438 countsByYear W20765844382015 @default.
• W2076584438 countsByYear W20765844382016 @default.
• W2076584438 countsByYear W20765844382017 @default.
• W2076584438 countsByYear W20765844382018 @default.
• W2076584438 countsByYear W20765844382019 @default.
• W2076584438 countsByYear W20765844382020 @default.
• W2076584438 countsByYear W20765844382021 @default.
• W2076584438 countsByYear W20765844382022 @default.
• W2076584438 countsByYear W20765844382023 @default.
• W2076584438 crossrefType "journal-article" @default.
• W2076584438 hasAuthorship W2076584438A5001153538 @default.
• W2076584438 hasAuthorship W2076584438A5004771945 @default.
• W2076584438 hasAuthorship W2076584438A5062987221 @default.
• W2076584438 hasAuthorship W2076584438A5072012950 @default.
• W2076584438 hasAuthorship W2076584438A5089559746 @default.
• W2076584438 hasConcept C111696902 @default.
• W2076584438 hasConcept C115537861 @default.
• W2076584438 hasConcept C11960822 @default.
• W2076584438 hasConcept C147789679 @default.
• W2076584438 hasConcept C178790620 @default.
• W2076584438 hasConcept C185592680 @default.
• W2076584438 hasConcept C199289684 @default.
• W2076584438 hasConcept C2777746296 @default.
• W2076584438 hasConcept C537208039 @default.
• W2076584438 hasConcept C55493867 @default.
• W2076584438 hasConcept C75217442 @default.
• W2076584438 hasConceptScore W2076584438C111696902 @default.
• W2076584438 hasConceptScore W2076584438C115537861 @default.
• W2076584438 hasConceptScore W2076584438C11960822 @default.
• W2076584438 hasConceptScore W2076584438C147789679 @default.
• W2076584438 hasConceptScore W2076584438C178790620 @default.
• W2076584438 hasConceptScore W2076584438C185592680 @default.
• W2076584438 hasConceptScore W2076584438C199289684 @default.
• W2076584438 hasConceptScore W2076584438C2777746296 @default.
• W2076584438 hasConceptScore W2076584438C537208039 @default.
• W2076584438 hasConceptScore W2076584438C55493867 @default.
• W2076584438 hasConceptScore W2076584438C75217442 @default.
• W2076584438 hasIssue "9" @default.
• W2076584438 hasLocation W20765844381 @default.
• W2076584438 hasLocation W20765844382 @default.
• W2076584438 hasOpenAccess W2076584438 @default.

• next