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• W2076609570 abstract "Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder characterised by seizures, mental retardation and hamartoma formation in multiple organs, mainly in the brain, skin, kidney, liver, lung and heart. Renal manifestations occur in about 60-80% of all patients with TSC and their rate increases with age. We report the case of a 17-year-old boy with tuberous sclerosis who presented with abdominal pain associated with kidney failure. Investigation revealed bilateral renal lesions, suggesting angiomyolipomas. On further work-up, malignancy was suspected and the patient underwent bilateral partial nephrectomy with histological diagnosis of bilateral renal cell carcinoma. This is a rare complication of TSC, particularly in a paediatric setting. Adequate surveillance of kidney disorders in patients with TSC is warranted, to guarantee an early diagnosis and treatment." @default.
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• W2076609570 date "2013-07-12" @default.
• W2076609570 modified "2023-10-17" @default.
• W2076609570 title "Bilateral renal cell carcinoma in a paediatric patient with tuberous sclerosis complex" @default.
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• W2076609570 doi "https://doi.org/10.1136/bcr-2013-010015" @default.
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