Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076619782> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2076619782 endingPage "207" @default.
- W2076619782 startingPage "203" @default.
- W2076619782 abstract "A placebo or methylprednisolone (45-60 mg/M2) was administered in a crossover study as a single morning dose on alternate days to fourteen patients who had a familial progressive polyneuropathy that either began or was maximum in the distribution of the peroneal nerves. Neither the patients nor the examining physician were told whether the patient was taking a placebo or steroid but the steroid side-effects made a double-blind trial impossible. Patients were evaluated at the initiation of the study, the time of crossover, and at the conclusion of the study. Five patients with proven HMSN-I completed the study; eight patients with HMSN-I were placed on a placebo or on steroids for a six-month-period. In neither group was there any evidence of a significant increase in nerve conduction times, a decrease in terminal latencies, an increase in strength or a decrease in sensory loss when evaluated by quantitative methods. These patients were subject to a high incidence of complications from steroids possibly because of root hypertrophy, relative inactivity, and high CSF proteins. These included excessive weight gain, a compression fracture of T-12; cord compression from enlarged nerve roots; myopathy; pseudotumor; and psychiatric disturbances. Considering the lack of benefit of steroids and the high incidence of complications due to the medication further trials of adrenal-corticosteroids in patients who definitely have familial HMSN-I do not seem to be justified." @default.
- W2076619782 created "2016-06-24" @default.
- W2076619782 creator A5027275480 @default.
- W2076619782 creator A5085225742 @default.
- W2076619782 date "1984-10-01" @default.
- W2076619782 modified "2023-09-27" @default.
- W2076619782 title "The Steroid Treatment of Hereditary Motor and Sensory Neuropathy" @default.
- W2076619782 doi "https://doi.org/10.1055/s-2008-1052367" @default.
- W2076619782 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6092990" @default.
- W2076619782 hasPublicationYear "1984" @default.
- W2076619782 type Work @default.
- W2076619782 sameAs 2076619782 @default.
- W2076619782 citedByCount "13" @default.
- W2076619782 countsByYear W20766197822015 @default.
- W2076619782 crossrefType "journal-article" @default.
- W2076619782 hasAuthorship W2076619782A5027275480 @default.
- W2076619782 hasAuthorship W2076619782A5085225742 @default.
- W2076619782 hasConcept C120665830 @default.
- W2076619782 hasConcept C121332964 @default.
- W2076619782 hasConcept C126322002 @default.
- W2076619782 hasConcept C141071460 @default.
- W2076619782 hasConcept C142724271 @default.
- W2076619782 hasConcept C204787440 @default.
- W2076619782 hasConcept C27081682 @default.
- W2076619782 hasConcept C2775892965 @default.
- W2076619782 hasConcept C2778970341 @default.
- W2076619782 hasConcept C2780372218 @default.
- W2076619782 hasConcept C42219234 @default.
- W2076619782 hasConcept C61511704 @default.
- W2076619782 hasConcept C71924100 @default.
- W2076619782 hasConcept C87813604 @default.
- W2076619782 hasConceptScore W2076619782C120665830 @default.
- W2076619782 hasConceptScore W2076619782C121332964 @default.
- W2076619782 hasConceptScore W2076619782C126322002 @default.
- W2076619782 hasConceptScore W2076619782C141071460 @default.
- W2076619782 hasConceptScore W2076619782C142724271 @default.
- W2076619782 hasConceptScore W2076619782C204787440 @default.
- W2076619782 hasConceptScore W2076619782C27081682 @default.
- W2076619782 hasConceptScore W2076619782C2775892965 @default.
- W2076619782 hasConceptScore W2076619782C2778970341 @default.
- W2076619782 hasConceptScore W2076619782C2780372218 @default.
- W2076619782 hasConceptScore W2076619782C42219234 @default.
- W2076619782 hasConceptScore W2076619782C61511704 @default.
- W2076619782 hasConceptScore W2076619782C71924100 @default.
- W2076619782 hasConceptScore W2076619782C87813604 @default.
- W2076619782 hasIssue "04" @default.
- W2076619782 hasLocation W20766197821 @default.
- W2076619782 hasLocation W20766197822 @default.
- W2076619782 hasOpenAccess W2076619782 @default.
- W2076619782 hasPrimaryLocation W20766197821 @default.
- W2076619782 hasRelatedWork W2003938723 @default.
- W2076619782 hasRelatedWork W2047967234 @default.
- W2076619782 hasRelatedWork W2075483136 @default.
- W2076619782 hasRelatedWork W2118496982 @default.
- W2076619782 hasRelatedWork W2275480158 @default.
- W2076619782 hasRelatedWork W2364998975 @default.
- W2076619782 hasRelatedWork W2369162477 @default.
- W2076619782 hasRelatedWork W2439875401 @default.
- W2076619782 hasRelatedWork W4238867864 @default.
- W2076619782 hasRelatedWork W2525756941 @default.
- W2076619782 hasVolume "15" @default.
- W2076619782 isParatext "false" @default.
- W2076619782 isRetracted "false" @default.
- W2076619782 magId "2076619782" @default.
- W2076619782 workType "article" @default.