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- W2076620612 abstract "The structure of CACNA1I, the gene encoding α1I, a human brain T Ca2+ channel α1 subunit, was determined by comparison of polymerase chain reaction-amplified brain cDNA and genomic sequences. The gene consists of at least 36 exons spanning at least 115 168 basepairs of chromosome 22q12.3–13.2. The predicted protein has 2016 amino acids and 28 potential phosphorylation sites. Alternative splicing of the gene occurs at two sites: cassette exon 9 and an alternative acceptor in exon 33. Molecular diversity generated by alternative splicing and post-translational modification of this and other members of the T α1 subunit gene family may account for the observed heterogeneity of T currents in central neurons." @default.
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- W2076620612 date "1999-07-01" @default.
- W2076620612 modified "2023-10-03" @default.
- W2076620612 title "Structure and alternative splicing of the gene encoding α1I, a human brain T calcium channel α1 subunit" @default.
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- W2076620612 doi "https://doi.org/10.1016/s0304-3940(99)00319-5" @default.
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