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- W2076625315 abstract "Objective Patients in the neonatal intensive care unit require life support and monitoringequipment that must be securely attached to the skin; removal or replacement often causes skin trauma. In this study, we compared the effects of application and removal of three different adhesives on the skin barrier function of premature neonates. The effects were measured by transepidermal water loss (TEWL), colorimetric measurements, and visual inspection. Design Thirty neonates, between 26 and 40 weeks of gestational age and with birth weights ranging from 690 to 3000 gm, were enrolled in the study during the first week of life. Pieces of plastic tape (1 cm 2 ), pectin barrier, and hydrophilic gel were applied to previously undisturbed sites on the back. A fourth site was used as a control. We measured TEWL, colorimetric readings, and visual inspection scores of skin irritation and stripping at each of the four sites serially: before adhesive application, 30 minutes after adhesive removal, and 24 hours later. Results Thirty minutes after adhesive removal, TEWL, colorimetric measurements, and visual inspection scores were all significantly higher at the sites of plastic tape and pectin barrier removal than at the control and gel adhesive sites (p" @default.
- W2076625315 created "2016-06-24" @default.
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- W2076625315 date "1998-07-01" @default.
- W2076625315 modified "2023-10-14" @default.
- W2076625315 title "Disruption of Barrier Function in Neonatal Skin Associated With Adhesive Removal" @default.
- W2076625315 doi "https://doi.org/10.1016/s0022-5347(01)63146-x" @default.
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