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- W2076639268 abstract "Fetal uptakes of amino acids and ammonia via the umbilical circulation were measured in single pregnant ewes at mid-gestation (range 66-81 days). There were significant net fluxes from placenta to fetus of ammonia and twelve amino acids (in decreasing order: glutamine, glycine, alanine, proline, lysine, arginine, threonine, valine, leucine, tyrosine, asparagine, isoleucine) and net fluxes from fetus to placenta of glutamate and serine. The estimated serine flux was 139 µmol day−1 (g fetal dry wt)−1. Comparison with late gestation data indicated a similar pattern of amino acid exchange. However, the relatively large placental uptake of fetal serine was a distinctive feature of mid-gestation. The net fetal uptake of amino acid nitrogen was 2·83 ± 0·66 µg N (µmol O2 uptake)−1, or 18 mg N day−1 (g dry wt)−. This uptake was similar in magnitude to the combined fetal requirements for nitrogen accretion and urea synthesis and represented approximately 32 and 43% of fetal carbon and energy requirements, respectively." @default.
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- W2076639268 date "1989-09-25" @default.
- W2076639268 modified "2023-09-27" @default.
- W2076639268 title "UPTAKE OF AMINO ACIDS AND AMMONIA AT MID-GESTATION BY THE FETAL LAMB" @default.
- W2076639268 doi "https://doi.org/10.1113/expphysiol.1989.sp003316" @default.
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