Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076657944> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2076657944 endingPage "1077" @default.
- W2076657944 startingPage "1072" @default.
- W2076657944 abstract "The in vitro activity of the dual-action antibacterial agent Ro 23-9424 was compared with those of cefotaxime, ceftazidime, ciprofloxacin, fleroxacin, imipenem, and amikacin against 358 aerobes and anaerobes. The MIC ranges, MICs for 50 and 90% of the strains (MIC50s and MIC90s), and percentage of strains susceptible for each agent at the recommended susceptible MIC breakpoint were determined for each genus. The MIC90s (micrograms per milliliter) of the agents against members of the family Enterobacteriaceae were as follows: ciprofloxacin, 0.063; Ro 23-9424, fleroxacin, and imipenem, 0.5; ceftazidime, 2; amikacin, 4; and cefotaxime, 16. The MIC90s (micrograms per milliliter) against Pseudomonas and Acinetobacter spp. were as follows: ciprofloxacin, 2; ceftazidime and imipenem, 8; Ro 23-9424, 16; fleroxacin, 32; amikacin, 64; and cefotaxime, 128. Against gram-positive bacteria, excluding the enterococci, the MIC90s (micrograms per milliliter) were as follows: ciprofloxacin, 1; imipenem, 4; Ro 23-9424 and fleroxacin, 8; amikacin, 64; and ceftazidime and cefotaxime, greater than 128. Against gram-positive bacteria, including the enterococci, the MIC90s changed only for the following agents: Ro 23-9424, 16 micrograms/ml; and amikacin, 128 micrograms/ml. Strains of Branhamella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae were 100% susceptible to Ro 23-9424, cefotaxime, ciprofloxacin, and fleroxacin, while the other three agents showed somewhat less activity only against N. gonorrhoeae. Against anaerobes, imipenem was the most effective agent, while the activities of the other six agents were variable." @default.
- W2076657944 created "2016-06-24" @default.
- W2076657944 creator A5036058226 @default.
- W2076657944 creator A5049547259 @default.
- W2076657944 creator A5056407273 @default.
- W2076657944 creator A5057434707 @default.
- W2076657944 creator A5058420420 @default.
- W2076657944 creator A5066893169 @default.
- W2076657944 creator A5067359034 @default.
- W2076657944 creator A5087947325 @default.
- W2076657944 date "1989-07-01" @default.
- W2076657944 modified "2023-10-14" @default.
- W2076657944 title "In vitro activities of a dual-action antibacterial agent, Ro 23-9424, and comparative agents" @default.
- W2076657944 cites W1549521446 @default.
- W2076657944 cites W1967517081 @default.
- W2076657944 cites W2035648196 @default.
- W2076657944 cites W2044477977 @default.
- W2076657944 cites W2058692136 @default.
- W2076657944 cites W2160994993 @default.
- W2076657944 doi "https://doi.org/10.1128/aac.33.7.1072" @default.
- W2076657944 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/176064" @default.
- W2076657944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2782857" @default.
- W2076657944 hasPublicationYear "1989" @default.
- W2076657944 type Work @default.
- W2076657944 sameAs 2076657944 @default.
- W2076657944 citedByCount "20" @default.
- W2076657944 countsByYear W20766579442014 @default.
- W2076657944 countsByYear W20766579442021 @default.
- W2076657944 crossrefType "journal-article" @default.
- W2076657944 hasAuthorship W2076657944A5036058226 @default.
- W2076657944 hasAuthorship W2076657944A5049547259 @default.
- W2076657944 hasAuthorship W2076657944A5056407273 @default.
- W2076657944 hasAuthorship W2076657944A5057434707 @default.
- W2076657944 hasAuthorship W2076657944A5058420420 @default.
- W2076657944 hasAuthorship W2076657944A5066893169 @default.
- W2076657944 hasAuthorship W2076657944A5067359034 @default.
- W2076657944 hasAuthorship W2076657944A5087947325 @default.
- W2076657944 hasBestOaLocation W20766579441 @default.
- W2076657944 hasConcept C2776968632 @default.
- W2076657944 hasConcept C2777316974 @default.
- W2076657944 hasConcept C2777427914 @default.
- W2076657944 hasConcept C2777637488 @default.
- W2076657944 hasConcept C2778049240 @default.
- W2076657944 hasConcept C2778512257 @default.
- W2076657944 hasConcept C2778523567 @default.
- W2076657944 hasConcept C2778719061 @default.
- W2076657944 hasConcept C2779631663 @default.
- W2076657944 hasConcept C3019249092 @default.
- W2076657944 hasConcept C501593827 @default.
- W2076657944 hasConcept C523546767 @default.
- W2076657944 hasConcept C54355233 @default.
- W2076657944 hasConcept C86803240 @default.
- W2076657944 hasConcept C89423630 @default.
- W2076657944 hasConcept C94665300 @default.
- W2076657944 hasConceptScore W2076657944C2776968632 @default.
- W2076657944 hasConceptScore W2076657944C2777316974 @default.
- W2076657944 hasConceptScore W2076657944C2777427914 @default.
- W2076657944 hasConceptScore W2076657944C2777637488 @default.
- W2076657944 hasConceptScore W2076657944C2778049240 @default.
- W2076657944 hasConceptScore W2076657944C2778512257 @default.
- W2076657944 hasConceptScore W2076657944C2778523567 @default.
- W2076657944 hasConceptScore W2076657944C2778719061 @default.
- W2076657944 hasConceptScore W2076657944C2779631663 @default.
- W2076657944 hasConceptScore W2076657944C3019249092 @default.
- W2076657944 hasConceptScore W2076657944C501593827 @default.
- W2076657944 hasConceptScore W2076657944C523546767 @default.
- W2076657944 hasConceptScore W2076657944C54355233 @default.
- W2076657944 hasConceptScore W2076657944C86803240 @default.
- W2076657944 hasConceptScore W2076657944C89423630 @default.
- W2076657944 hasConceptScore W2076657944C94665300 @default.
- W2076657944 hasIssue "7" @default.
- W2076657944 hasLocation W20766579441 @default.
- W2076657944 hasLocation W20766579442 @default.
- W2076657944 hasLocation W20766579443 @default.
- W2076657944 hasOpenAccess W2076657944 @default.
- W2076657944 hasPrimaryLocation W20766579441 @default.
- W2076657944 hasRelatedWork W1987327841 @default.
- W2076657944 hasRelatedWork W2003131043 @default.
- W2076657944 hasRelatedWork W2077282632 @default.
- W2076657944 hasRelatedWork W2153252267 @default.
- W2076657944 hasRelatedWork W2351323778 @default.
- W2076657944 hasRelatedWork W2351680346 @default.
- W2076657944 hasRelatedWork W2410761020 @default.
- W2076657944 hasRelatedWork W2418943397 @default.
- W2076657944 hasRelatedWork W2465833206 @default.
- W2076657944 hasRelatedWork W3004577790 @default.
- W2076657944 hasVolume "33" @default.
- W2076657944 isParatext "false" @default.
- W2076657944 isRetracted "false" @default.
- W2076657944 magId "2076657944" @default.
- W2076657944 workType "article" @default.