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- W2076674887 abstract "Swiss albino mice exposed to 5 and 10 mg diethylnitrosamine kg−1 body weight by intravenous route up to four weeks showed cyto- and genotoxic effects. Distortion of cell and nucleus shapes and extensive necrosis were observed. Thymidine kinase activity in the liver declined in diethylnitrosamine dose and duration dependent manners. The adult-form of thymidine kinase isozyme declined continuously during this period. Simultaneously, two isozymic forms of thymidine kinase, with small anodic migrations in an electrophoretic field, were gradually induced. Significance of these changes in diethylnitrosamine induced precarcinogenic toxicity has been discussed." @default.
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- W2076674887 title "Low dose exposure of diethylnitrosamine affects mice liver thymidine kinase" @default.
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- W2076674887 doi "https://doi.org/10.1016/0024-3205(95)02261-2" @default.
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