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- W2076676329 abstract "Abstract IgG4-related disease usually presents with a mass-forming or regional lesion showing considerable lymphoplasmacytic infiltration with many IgG4-positive plasma cells, sclerosis, and obliterative phlebitis. Herein, recent progress of hepatobiliary IgG4-related diseases including IgG4-related sclerosing cholangitis (IgG4-SC), hepatic inflammatory pseudotumor (HIP), and autoimmune hepatitis (AIH), are reviewed. IgG4-SC mainly affects the extrahepatic and hilar bile ducts, and is almost always associated with autoimmune pancreatitis (AIP), a prototype of IgG4-related disease. IgG4-SC has a propensity to exaggerate focally, and such IgG4-SC could be categorized as an IgG4-related HIP, mainly belonging to the lymphoplasmacytic type of HIP. IgG4-related AIH is a chronic active hepatitis with many IgG4-positive plasma cells and increased serum IgG4 level. In conclusion, several hepatobiliary diseases which had been diagnosed as other diseases, can be reclassified as IgG4-related diseases, and several local factors peculiar to the hepatobiliary system may be responsible for the development of these diseases." @default.
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- W2076676329 date "2011-10-01" @default.
- W2076676329 modified "2023-09-26" @default.
- W2076676329 title "Recent progress of IgG4-related hepatobiliary diseases with emphasis on pathologic aspects and differential diagnosis" @default.
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- W2076676329 doi "https://doi.org/10.1016/j.mpdhp.2011.06.010" @default.
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