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• W2076750539 abstract "Abstract As shown in previous papers, mathematical simulation can be useful in the design of drug delivery systems. We present a finite-difference approximation to the drug mass transfer rate from dissolving cylindrical drug-containing compacts, consisting of alternating layers of drug and inert material. Results are compared with a recent analytical solution to the same problem and with experiment. The two theoretical estimates differ by about 10%, a result of different implementations of a derivative surface boundary condition. The finite-difference model is more physically realistic but the analytical solution is usefully accurate." @default.
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• W2076750539 date "2007-03-01" @default.
• W2076750539 modified "2023-09-26" @default.
• W2076750539 title "The importance of boundary conditions in the simulation of dissolution in the USP dissolution apparatus" @default.
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• W2076750539 doi "https://doi.org/10.1016/j.simpat.2007.01.003" @default.
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