FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076751432> ?p ?o ?g. }

• W2076751432 endingPage "593" @default.
• W2076751432 startingPage "587" @default.
• W2076751432 abstract "Mercury (Hg) impairs glutamate homeostasis but little is known about its effects on the N-methyl-d-aspartic acid (NMDA) receptor. Here, we investigated NMDA receptor levels, as determined by [(3)H]-MK801 binding, in both wild and captive mink (Mustela vison) that experienced different levels of methylmercury (MeHg) exposure. Competitive in vitro binding experiments showed that inorganic Hg (HgCl(2); IC(50)=1.5-20.7 microM), but not MeHg (MeHgCl; IC(50)>320 microM), inhibited binding to the NMDA receptor in several brain regions of mink. In a survey of trapped wild mink, NMDA receptor levels in the brain were negatively correlated (p<0.005) with concentrations of total Hg (R=-0.618) and MeHg (R=-0.714). These findings were supported by a laboratory feeding study in which captive mink were exposed to dietary MeHg (0-2 ppm) for 89 days. Concentration-dependent decreases in NMDA receptor levels were found in the basal ganglia, cerebellum, brain stem and occipital cortex. These findings are of physiological and ecological concern because they demonstrate that Hg, at dietary concentrations as low as 0.1 ppm, can significantly reduce NMDA receptor levels." @default.
• W2076751432 created "2016-06-24" @default.
• W2076751432 creator A5017456307 @default.
• W2076751432 creator A5018327817 @default.
• W2076751432 creator A5025182060 @default.
• W2076751432 creator A5041417946 @default.
• W2076751432 creator A5057772177 @default.
• W2076751432 creator A5089429080 @default.
• W2076751432 creator A5090836175 @default.
• W2076751432 date "2007-05-01" @default.
• W2076751432 modified "2023-10-02" @default.
• W2076751432 title "Decreased N-methyl-d-aspartic acid (NMDA) receptor levels are associated with mercury exposure in wild and captive mink" @default.
• W2076751432 cites W1909014930 @default.
• W2076751432 cites W1970577590 @default.
• W2076751432 cites W1972684978 @default.
• W2076751432 cites W1975432299 @default.
• W2076751432 cites W1976289522 @default.
• W2076751432 cites W1985708141 @default.
• W2076751432 cites W1999379012 @default.
• W2076751432 cites W2011822918 @default.
• W2076751432 cites W2013706308 @default.
• W2076751432 cites W2017522100 @default.
• W2076751432 cites W2031338620 @default.
• W2076751432 cites W2031428267 @default.
• W2076751432 cites W2040119565 @default.
• W2076751432 cites W2044943309 @default.
• W2076751432 cites W2047305032 @default.
• W2076751432 cites W2061790070 @default.
• W2076751432 cites W2063700856 @default.
• W2076751432 cites W2064857569 @default.
• W2076751432 cites W2067374933 @default.
• W2076751432 cites W2068788889 @default.
• W2076751432 cites W2069695212 @default.
• W2076751432 cites W2070904317 @default.
• W2076751432 cites W2071771485 @default.
• W2076751432 cites W2081900803 @default.
• W2076751432 cites W2094850331 @default.
• W2076751432 cites W2111062311 @default.
• W2076751432 cites W2159545629 @default.
• W2076751432 cites W2164674870 @default.
• W2076751432 cites W2168367599 @default.
• W2076751432 cites W2171607926 @default.
• W2076751432 cites W2172098894 @default.
• W2076751432 cites W2316145923 @default.
• W2076751432 cites W238548312 @default.
• W2076751432 doi "https://doi.org/10.1016/j.neuro.2006.12.007" @default.
• W2076751432 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17267038" @default.
• W2076751432 hasPublicationYear "2007" @default.
• W2076751432 type Work @default.
• W2076751432 sameAs 2076751432 @default.
• W2076751432 citedByCount "78" @default.
• W2076751432 countsByYear W20767514322012 @default.
• W2076751432 countsByYear W20767514322013 @default.
• W2076751432 countsByYear W20767514322014 @default.
• W2076751432 countsByYear W20767514322015 @default.
• W2076751432 countsByYear W20767514322016 @default.
• W2076751432 countsByYear W20767514322017 @default.
• W2076751432 countsByYear W20767514322018 @default.
• W2076751432 countsByYear W20767514322019 @default.
• W2076751432 countsByYear W20767514322020 @default.
• W2076751432 countsByYear W20767514322021 @default.
• W2076751432 countsByYear W20767514322022 @default.
• W2076751432 countsByYear W20767514322023 @default.
• W2076751432 crossrefType "journal-article" @default.
• W2076751432 hasAuthorship W2076751432A5017456307 @default.
• W2076751432 hasAuthorship W2076751432A5018327817 @default.
• W2076751432 hasAuthorship W2076751432A5025182060 @default.
• W2076751432 hasAuthorship W2076751432A5041417946 @default.
• W2076751432 hasAuthorship W2076751432A5057772177 @default.
• W2076751432 hasAuthorship W2076751432A5089429080 @default.
• W2076751432 hasAuthorship W2076751432A5090836175 @default.
• W2076751432 hasConcept C126322002 @default.
• W2076751432 hasConcept C134018914 @default.
• W2076751432 hasConcept C170493617 @default.
• W2076751432 hasConcept C185592680 @default.
• W2076751432 hasConcept C18903297 @default.
• W2076751432 hasConcept C2779652256 @default.
• W2076751432 hasConcept C2780373914 @default.
• W2076751432 hasConcept C2780648746 @default.
• W2076751432 hasConcept C2780754187 @default.
• W2076751432 hasConcept C2781208047 @default.
• W2076751432 hasConcept C515207424 @default.
• W2076751432 hasConcept C55493867 @default.
• W2076751432 hasConcept C61174792 @default.
• W2076751432 hasConcept C67018056 @default.
• W2076751432 hasConcept C71572567 @default.
• W2076751432 hasConcept C71924100 @default.
• W2076751432 hasConcept C86803240 @default.
• W2076751432 hasConceptScore W2076751432C126322002 @default.
• W2076751432 hasConceptScore W2076751432C134018914 @default.
• W2076751432 hasConceptScore W2076751432C170493617 @default.
• W2076751432 hasConceptScore W2076751432C185592680 @default.
• W2076751432 hasConceptScore W2076751432C18903297 @default.
• W2076751432 hasConceptScore W2076751432C2779652256 @default.
• W2076751432 hasConceptScore W2076751432C2780373914 @default.
• W2076751432 hasConceptScore W2076751432C2780648746 @default.
• W2076751432 hasConceptScore W2076751432C2780754187 @default.
• W2076751432 hasConceptScore W2076751432C2781208047 @default.

• next