Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076751971> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2076751971 endingPage "S602" @default.
- W2076751971 startingPage "S602" @default.
- W2076751971 abstract "Drug addiction is one of the leading causes of mortality worldwide. Despite great advances were achieved in understanding the neurobiology of drug addiction, the therapeutic options are severely limited, with poor effectiveness and serious side effects. The neuropeptide oxytocin (OXT) is well known for its effects on uterine contraction, sexual/maternal behaviors, social affiliation, stress and learning/memory by interacting with the OXT receptor and other neuromodulators. Emerging evidence suggests that the acute or chronic exposure to drugs can affect the OXT system. Additionally, OXT administration can ameliorate a wide range of abused drug-induced neurobehavioral changes. Overall, OXT not only suppresses drug reward in the binge stage of drug addiction, but also reduces stress responses and social impairments during the withdrawal stage and, finally, prevents drug/cue/stress-induced reinstatement. More importantly, clinical studies have also shown that OXT can exert beneficial effects on reducing substance use disorders of a series of drugs, such as heroin, cocaine, alcohol, cannabis and nicotine. Thus, the present review focuses on the role of OXT in treating drug addiction, including the preclinical and clinical therapeutic potential of OXT and its analogs on the neurobiological perspectives of drugs, to provide a better insight of the efficacy of OXT as a clinical addiction therapeutic agent." @default.
- W2076751971 created "2016-06-24" @default.
- W2076751971 creator A5002410074 @default.
- W2076751971 creator A5012741427 @default.
- W2076751971 creator A5023892471 @default.
- W2076751971 creator A5029080306 @default.
- W2076751971 creator A5030054670 @default.
- W2076751971 creator A5090003238 @default.
- W2076751971 date "2014-10-01" @default.
- W2076751971 modified "2023-09-24" @default.
- W2076751971 title "P.4.b.026 Intranasal oxytocin modulates neural processing of emotional faces in recently traumatised individuals at increased risk for PTSD" @default.
- W2076751971 doi "https://doi.org/10.1016/s0924-977x(14)70965-4" @default.
- W2076751971 hasPublicationYear "2014" @default.
- W2076751971 type Work @default.
- W2076751971 sameAs 2076751971 @default.
- W2076751971 citedByCount "1" @default.
- W2076751971 countsByYear W20767519712022 @default.
- W2076751971 crossrefType "journal-article" @default.
- W2076751971 hasAuthorship W2076751971A5002410074 @default.
- W2076751971 hasAuthorship W2076751971A5012741427 @default.
- W2076751971 hasAuthorship W2076751971A5023892471 @default.
- W2076751971 hasAuthorship W2076751971A5029080306 @default.
- W2076751971 hasAuthorship W2076751971A5030054670 @default.
- W2076751971 hasAuthorship W2076751971A5090003238 @default.
- W2076751971 hasConcept C118303440 @default.
- W2076751971 hasConcept C118552586 @default.
- W2076751971 hasConcept C126322002 @default.
- W2076751971 hasConcept C15744967 @default.
- W2076751971 hasConcept C169760540 @default.
- W2076751971 hasConcept C170493617 @default.
- W2076751971 hasConcept C2776176026 @default.
- W2076751971 hasConcept C2777056318 @default.
- W2076751971 hasConcept C2778903686 @default.
- W2076751971 hasConcept C2779547902 @default.
- W2076751971 hasConcept C2780035454 @default.
- W2076751971 hasConcept C2780376393 @default.
- W2076751971 hasConcept C48856860 @default.
- W2076751971 hasConcept C71924100 @default.
- W2076751971 hasConcept C98274493 @default.
- W2076751971 hasConceptScore W2076751971C118303440 @default.
- W2076751971 hasConceptScore W2076751971C118552586 @default.
- W2076751971 hasConceptScore W2076751971C126322002 @default.
- W2076751971 hasConceptScore W2076751971C15744967 @default.
- W2076751971 hasConceptScore W2076751971C169760540 @default.
- W2076751971 hasConceptScore W2076751971C170493617 @default.
- W2076751971 hasConceptScore W2076751971C2776176026 @default.
- W2076751971 hasConceptScore W2076751971C2777056318 @default.
- W2076751971 hasConceptScore W2076751971C2778903686 @default.
- W2076751971 hasConceptScore W2076751971C2779547902 @default.
- W2076751971 hasConceptScore W2076751971C2780035454 @default.
- W2076751971 hasConceptScore W2076751971C2780376393 @default.
- W2076751971 hasConceptScore W2076751971C48856860 @default.
- W2076751971 hasConceptScore W2076751971C71924100 @default.
- W2076751971 hasConceptScore W2076751971C98274493 @default.
- W2076751971 hasLocation W20767519711 @default.
- W2076751971 hasOpenAccess W2076751971 @default.
- W2076751971 hasPrimaryLocation W20767519711 @default.
- W2076751971 hasRelatedWork W112700641 @default.
- W2076751971 hasRelatedWork W1986499151 @default.
- W2076751971 hasRelatedWork W2169040097 @default.
- W2076751971 hasRelatedWork W2366518417 @default.
- W2076751971 hasRelatedWork W2416004696 @default.
- W2076751971 hasRelatedWork W2566039628 @default.
- W2076751971 hasRelatedWork W3127592000 @default.
- W2076751971 hasRelatedWork W3130700614 @default.
- W2076751971 hasRelatedWork W3135513407 @default.
- W2076751971 hasRelatedWork W3200287574 @default.
- W2076751971 hasVolume "24" @default.
- W2076751971 isParatext "false" @default.
- W2076751971 isRetracted "false" @default.
- W2076751971 magId "2076751971" @default.
- W2076751971 workType "article" @default.