FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076752406> ?p ?o ?g. }

• W2076752406 endingPage "1115" @default.
• W2076752406 startingPage "1111" @default.
• W2076752406 abstract "Long-term treatment with appropriate doses of carvedilol or metoprolol is currently recommended for patients with heart failure with reduced ejection fraction (HFrEF) to decrease the risk of death, hospitalizations, and patients' symptoms. It remains unclear if the β blockers used in patients with HFrEF are equal or carvedilol is superior to metoprolol types. We performed a meta-analysis of the comparative effects of carvedilol versus metoprolol tartrate and succinate on all-cause mortality and/or hospitalization. We conducted an Embase and MEDLINE search for prospective controlled trials and cohort studies of patients with HFrEF who were received to treatment with carvedilol versus metoprolol. We identified 4 prospective controlled and 6 cohort studies with 30,943 patients who received carvedilol and 69,925 patients on metoprolol types (tartrate and succinate) with an average follow-up duration of 36.4 months. All-cause mortality was reduced in prospective studies with carvedilol versus metoprolol tartrate. Neither all-cause mortality nor hospitalizations were significantly different between carvedilol and metoprolol succinate in the cohort studies. In conclusion, in patients with HFrEF, carvedilol and metoprolol succinate have similar effects in reducing all-cause mortality. Long-term treatment with appropriate doses of carvedilol or metoprolol is currently recommended for patients with heart failure with reduced ejection fraction (HFrEF) to decrease the risk of death, hospitalizations, and patients' symptoms. It remains unclear if the β blockers used in patients with HFrEF are equal or carvedilol is superior to metoprolol types. We performed a meta-analysis of the comparative effects of carvedilol versus metoprolol tartrate and succinate on all-cause mortality and/or hospitalization. We conducted an Embase and MEDLINE search for prospective controlled trials and cohort studies of patients with HFrEF who were received to treatment with carvedilol versus metoprolol. We identified 4 prospective controlled and 6 cohort studies with 30,943 patients who received carvedilol and 69,925 patients on metoprolol types (tartrate and succinate) with an average follow-up duration of 36.4 months. All-cause mortality was reduced in prospective studies with carvedilol versus metoprolol tartrate. Neither all-cause mortality nor hospitalizations were significantly different between carvedilol and metoprolol succinate in the cohort studies. In conclusion, in patients with HFrEF, carvedilol and metoprolol succinate have similar effects in reducing all-cause mortality." @default.
• W2076752406 created "2016-06-24" @default.
• W2076752406 creator A5053764173 @default.
• W2076752406 creator A5063483560 @default.
• W2076752406 creator A5064175292 @default.
• W2076752406 date "2015-04-01" @default.
• W2076752406 modified "2023-10-03" @default.
• W2076752406 title "Meta-Analysis of the Effects of Carvedilol Versus Metoprolol on All-Cause Mortality and Hospitalizations in Patients With Heart Failure" @default.
• W2076752406 cites W1525119409 @default.
• W2076752406 cites W1594418238 @default.
• W2076752406 cites W1605592151 @default.
• W2076752406 cites W1985697392 @default.
• W2076752406 cites W2030021373 @default.
• W2076752406 cites W2052240301 @default.
• W2076752406 cites W2060919765 @default.
• W2076752406 cites W2090053162 @default.
• W2076752406 cites W2095430292 @default.
• W2076752406 cites W2096685333 @default.
• W2076752406 cites W2098923148 @default.
• W2076752406 cites W2129967926 @default.
• W2076752406 cites W2154370947 @default.
• W2076752406 cites W2158635242 @default.
• W2076752406 cites W2163130289 @default.
• W2076752406 cites W2170505974 @default.
• W2076752406 cites W2178738676 @default.
• W2076752406 cites W2296998040 @default.
• W2076752406 cites W3023522280 @default.
• W2076752406 doi "https://doi.org/10.1016/j.amjcard.2015.01.545" @default.
• W2076752406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25708861" @default.
• W2076752406 hasPublicationYear "2015" @default.
• W2076752406 type Work @default.
• W2076752406 sameAs 2076752406 @default.
• W2076752406 citedByCount "22" @default.
• W2076752406 countsByYear W20767524062015 @default.
• W2076752406 countsByYear W20767524062017 @default.
• W2076752406 countsByYear W20767524062018 @default.
• W2076752406 countsByYear W20767524062019 @default.
• W2076752406 countsByYear W20767524062020 @default.
• W2076752406 countsByYear W20767524062021 @default.
• W2076752406 countsByYear W20767524062022 @default.
• W2076752406 crossrefType "journal-article" @default.
• W2076752406 hasAuthorship W2076752406A5053764173 @default.
• W2076752406 hasAuthorship W2076752406A5063483560 @default.
• W2076752406 hasAuthorship W2076752406A5064175292 @default.
• W2076752406 hasConcept C126322002 @default.
• W2076752406 hasConcept C164705383 @default.
• W2076752406 hasConcept C188816634 @default.
• W2076752406 hasConcept C201903717 @default.
• W2076752406 hasConcept C2778198053 @default.
• W2076752406 hasConcept C2780591200 @default.
• W2076752406 hasConcept C2781280847 @default.
• W2076752406 hasConcept C2909447574 @default.
• W2076752406 hasConcept C71924100 @default.
• W2076752406 hasConcept C72563966 @default.
• W2076752406 hasConcept C78085059 @default.
• W2076752406 hasConceptScore W2076752406C126322002 @default.
• W2076752406 hasConceptScore W2076752406C164705383 @default.
• W2076752406 hasConceptScore W2076752406C188816634 @default.
• W2076752406 hasConceptScore W2076752406C201903717 @default.
• W2076752406 hasConceptScore W2076752406C2778198053 @default.
• W2076752406 hasConceptScore W2076752406C2780591200 @default.
• W2076752406 hasConceptScore W2076752406C2781280847 @default.
• W2076752406 hasConceptScore W2076752406C2909447574 @default.
• W2076752406 hasConceptScore W2076752406C71924100 @default.
• W2076752406 hasConceptScore W2076752406C72563966 @default.
• W2076752406 hasConceptScore W2076752406C78085059 @default.
• W2076752406 hasIssue "8" @default.
• W2076752406 hasLocation W20767524061 @default.
• W2076752406 hasLocation W20767524062 @default.
• W2076752406 hasOpenAccess W2076752406 @default.
• W2076752406 hasPrimaryLocation W20767524061 @default.
• W2076752406 hasRelatedWork W1548375036 @default.
• W2076752406 hasRelatedWork W1758052586 @default.
• W2076752406 hasRelatedWork W2040815912 @default.
• W2076752406 hasRelatedWork W2076752406 @default.
• W2076752406 hasRelatedWork W2101735792 @default.
• W2076752406 hasRelatedWork W2145795038 @default.
• W2076752406 hasRelatedWork W2167036398 @default.
• W2076752406 hasRelatedWork W2386268122 @default.
• W2076752406 hasRelatedWork W2908280045 @default.
• W2076752406 hasRelatedWork W4234660475 @default.
• W2076752406 hasVolume "115" @default.
• W2076752406 isParatext "false" @default.
• W2076752406 isRetracted "false" @default.
• W2076752406 magId "2076752406" @default.
• W2076752406 workType "article" @default.