FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2076784848> ?p ?o ?g. }

• W2076784848 endingPage "170" @default.
• W2076784848 startingPage "165" @default.
• W2076784848 abstract "Early exposure to glucocorticoids (GC) has been proposed to disturb hepatic and cardiac function in later life. In the present study, we evaluated early metabolic alterations upon GC treatment that may predispose to long-term abnormalities. Rats were injected with dexamethasone (DEX) at d 1, 2, and 3 after birth and controls received saline (SAL). Rats were killed at 2, 7, and 14 d of age. Compared with SAL, DEX induced lower plasma insulin levels, hyperglycemia, hyperketonemia, and dyslipidemia at 2 d. At the same time, DEX treatment significantly increased expression of gluconeogenic and fatty acid oxidation genes in liver and expression of genes involved fatty acid utilization in heart. At 7 d, DEX-treated rats showed insulin resistance with hyperlipidemia, whereas hepatic and cardiac gene expression patterns were largely normalized. Hyperlipidemia and a significantly increased hepatic triglyceride content in DEX-treated rats were prominent at 14 d without large differences in hepatic and cardiac gene expression patterns. Thus, neonatal DEX administration transiently affects cardiac and hepatic gene expression patterns in suckling rats associated with sustained effects on plasma glucose and lipid concentrations. Whether these early effects of DEX contribute to hepatic and cardiac abnormalities at adult age needs further evaluation." @default.
• W2076784848 created "2016-06-24" @default.
• W2076784848 creator A5008713165 @default.
• W2076784848 creator A5021293751 @default.
• W2076784848 creator A5032174537 @default.
• W2076784848 creator A5035797344 @default.
• W2076784848 creator A5045489297 @default.
• W2076784848 creator A5046047916 @default.
• W2076784848 creator A5068012448 @default.
• W2076784848 creator A5087500433 @default.
• W2076784848 date "2007-02-01" @default.
• W2076784848 modified "2023-10-02" @default.
• W2076784848 title "Postnatal Treatment With Dexamethasone Perturbs Hepatic and Cardiac Energy Metabolism and Is Associated With a Sustained Atherogenic Plasma Lipid Profile in Suckling Rats" @default.
• W2076784848 cites W1577577364 @default.
• W2076784848 cites W1590787058 @default.
• W2076784848 cites W17332004 @default.
• W2076784848 cites W1760999968 @default.
• W2076784848 cites W1969834886 @default.
• W2076784848 cites W1977366037 @default.
• W2076784848 cites W1981847955 @default.
• W2076784848 cites W1988064154 @default.
• W2076784848 cites W1993254543 @default.
• W2076784848 cites W1995797667 @default.
• W2076784848 cites W1997891097 @default.
• W2076784848 cites W2004114946 @default.
• W2076784848 cites W2004577140 @default.
• W2076784848 cites W2004947549 @default.
• W2076784848 cites W200601437 @default.
• W2076784848 cites W2012920122 @default.
• W2076784848 cites W2024039041 @default.
• W2076784848 cites W2038120135 @default.
• W2076784848 cites W2047680032 @default.
• W2076784848 cites W2056777192 @default.
• W2076784848 cites W2070806823 @default.
• W2076784848 cites W2078075091 @default.
• W2076784848 cites W2093310517 @default.
• W2076784848 cites W2105362864 @default.
• W2076784848 cites W2109256570 @default.
• W2076784848 cites W2112038931 @default.
• W2076784848 cites W2115406697 @default.
• W2076784848 cites W2121370344 @default.
• W2076784848 cites W2136611430 @default.
• W2076784848 cites W2151959069 @default.
• W2076784848 cites W2152311269 @default.
• W2076784848 cites W2153887704 @default.
• W2076784848 cites W2168449556 @default.
• W2076784848 cites W2186068418 @default.
• W2076784848 cites W2238922603 @default.
• W2076784848 cites W2415048134 @default.
• W2076784848 cites W4233277454 @default.
• W2076784848 doi "https://doi.org/10.1203/pdr.0b013e31802d89ff" @default.
• W2076784848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17237716" @default.
• W2076784848 hasPublicationYear "2007" @default.
• W2076784848 type Work @default.
• W2076784848 sameAs 2076784848 @default.
• W2076784848 citedByCount "11" @default.
• W2076784848 countsByYear W20767848482013 @default.
• W2076784848 countsByYear W20767848482016 @default.
• W2076784848 countsByYear W20767848482017 @default.
• W2076784848 countsByYear W20767848482021 @default.
• W2076784848 countsByYear W20767848482022 @default.
• W2076784848 countsByYear W20767848482023 @default.
• W2076784848 crossrefType "journal-article" @default.
• W2076784848 hasAuthorship W2076784848A5008713165 @default.
• W2076784848 hasAuthorship W2076784848A5021293751 @default.
• W2076784848 hasAuthorship W2076784848A5032174537 @default.
• W2076784848 hasAuthorship W2076784848A5035797344 @default.
• W2076784848 hasAuthorship W2076784848A5045489297 @default.
• W2076784848 hasAuthorship W2076784848A5046047916 @default.
• W2076784848 hasAuthorship W2076784848A5068012448 @default.
• W2076784848 hasAuthorship W2076784848A5087500433 @default.
• W2076784848 hasBestOaLocation W20767848481 @default.
• W2076784848 hasConcept C111566952 @default.
• W2076784848 hasConcept C126322002 @default.
• W2076784848 hasConcept C134018914 @default.
• W2076784848 hasConcept C2777391703 @default.
• W2076784848 hasConcept C2778096610 @default.
• W2076784848 hasConcept C2778163477 @default.
• W2076784848 hasConcept C2778198053 @default.
• W2076784848 hasConcept C2778913445 @default.
• W2076784848 hasConcept C2779091943 @default.
• W2076784848 hasConcept C2779306644 @default.
• W2076784848 hasConcept C2780401358 @default.
• W2076784848 hasConcept C4733338 @default.
• W2076784848 hasConcept C555293320 @default.
• W2076784848 hasConcept C62231903 @default.
• W2076784848 hasConcept C71924100 @default.
• W2076784848 hasConcept C82714985 @default.
• W2076784848 hasConcept C86803240 @default.
• W2076784848 hasConceptScore W2076784848C111566952 @default.
• W2076784848 hasConceptScore W2076784848C126322002 @default.
• W2076784848 hasConceptScore W2076784848C134018914 @default.
• W2076784848 hasConceptScore W2076784848C2777391703 @default.
• W2076784848 hasConceptScore W2076784848C2778096610 @default.
• W2076784848 hasConceptScore W2076784848C2778163477 @default.
• W2076784848 hasConceptScore W2076784848C2778198053 @default.
• W2076784848 hasConceptScore W2076784848C2778913445 @default.
• W2076784848 hasConceptScore W2076784848C2779091943 @default.

• next