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- W2076805273 abstract "In a search for new therapeutic agents, a series of Mannich derivatives of 3-methyl-2-phenylindolizine and 3-ethyl-2-phenylindolizine has been prepared. The mechanism by which 2,3-disubstituted indolizines participate in the Mannich reaction has been examined and alternate SN1 and SN2 routes have been proposed. 1-Diethyl-aminomethyl-3-methyl-2-phenylindolizine has been tested and found to have central nervous system depressant activity. In a search for new therapeutic agents, a series of Mannich derivatives of 3-methyl-2-phenylindolizine and 3-ethyl-2-phenylindolizine has been prepared. The mechanism by which 2,3-disubstituted indolizines participate in the Mannich reaction has been examined and alternate SN1 and SN2 routes have been proposed. 1-Diethyl-aminomethyl-3-methyl-2-phenylindolizine has been tested and found to have central nervous system depressant activity." @default.
- W2076805273 created "2016-06-24" @default.
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- W2076805273 date "1967-02-01" @default.
- W2076805273 modified "2023-09-23" @default.
- W2076805273 title "Mannich Bases from 2-Phenylindolizines I" @default.
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- W2076805273 doi "https://doi.org/10.1002/jps.2600560215" @default.
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